ArticleFrontiers in oncology2026
Primary vaginal yolk sac tumor in an 11-month-old girl: a case report.
Article in Frontiers in oncology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Extragonadal yolk sac tumors are exceedingly rare. This report describes a vaginal yolk sac tumor in an infant to highlight key diagnostic and therapeutic aspects and its inclusion in the differential diagnoses of unexplained vaginal masses. Case presentation: An 11-month-old girl presented with intermittent vaginal bleeding, initially misdiagnosed as a hematoma. Pathological examination confirmed yolk sac tumors. She underwent hysteroscopic resection and six cycles of PEB (bleomycin, etoposide, cisplatin) chemotherapy. No recurrence occurred during the 12-month follow-up. Conclusion: Primary vaginal yolk sac tumors are extremely rare and lack standardized treatment. Surgery combined with PEB chemotherapy proved effective in this case.
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