ArticlePreventive medicine reports2026
Association between Sugar-sweetened beverage consumption and gallstones: A cross-sectional analysis from NHANES 2017-2023.
Article in Preventive medicine reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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4 authors.
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Abstract
Objective: Sugar-sweetened beverages (SSBs) are a major source of added sugars and may be related to gallstones, yet the quantitative relationship has not been well characterized. To evaluate the association between SSB consumption and gallstone prevalence, assess potential non-linear dose-response patterns, and exploratorily examine subgroup differences. Methods: We analyzed 9001 U.S. adults in National Health and Nutrition Examination Survey (NHANES) 2017-2023. SSB exposure was derived from two 24-h dietary recalls; gallstones were ascertained by self-report. Survey-weighted logistic regression estimated odds ratios (ORs) with progressive covariate adjustment. Non-linearity was tested using restricted cubic splines (RCS). Subgroup and sensitivity analyses were also performed. Results: Every 100 kcal/day increment in SSBs was associated with 10% higher odds of gallstones (adjusted OR = 1.10; 95% CI: 1.05, 1.15). Compared with non-consumers, ≥300 kcal/day related to an 81% higher odds (OR = 1.81; 95% CI: 1.37, 2.40). RCS indicated a significant non-linear relationship ( Conclusions: Higher SSB intake was positively and non-linearly associated with gallstone prevalence in this cross-sectional analysis. Longitudinal studies are warranted to confirm temporality and clarify underlying mechanisms.
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