ArticleJTO clinical and research reports2026
Long-Term Outcomes of Surgery for Thymic Epithelial Tumors With Pleural Metastases.
Article in JTO clinical and research reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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8 authors.
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Abstract
Background: Thymic epithelial tumors (TETs) are broadly classified into thymomas and thymic carcinomas (TC). These can present with pleural dissemination at diagnosis (TNM stage IVA) or as recurrence. As the benefit of resection or re-resection for stage IVA disease is unclear, we sought to identify factors affecting clinical outcomes. Methods: This single-institution case series includes patients with TET having pleural dissemination who underwent surgery between 2006 and 2022 for initial (S4) or recurrent (R4) stage IVA disease. The association between potential prognostic factors and survival was evaluated using Kaplan-Meier and Cox proportional hazard analyses. Results: A total of 71 patients underwent surgery for pleural metastases (median age 45 y, TC = 22, S4 = 44), with 43 (61%) receiving induction chemotherapy. Overall survival (OS) for S4 and R4 was 10.6 years and 5.7 years, respectively ( Conclusions: Surgical resection of stage IVA TETs is associated with greater survival benefit for thymomas compared with TC. Further studies should focus on associations between LN status and both OS and RFS, along with predictive biomarkers.
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