Evidence map›Paper›PMID 41869473›Full record

ArticleJournal of wrist surgery2026

Can Hyaluronic Acid Reduce Friction in the First Extensor Compartment? A Cadaveric Study.

Gilad Rotem, Emma Badowski, Matan J Cohen, G Daniel G Langohr, Assaf Kadar

Abstract read
In one paragraph

Article in Journal of wrist surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Gilad RotemUniversity of Western Ontario, Roth McFarlane Hand & Upper Limb Centre, St Joseph's Health Care, London, Ontario, Canada.ORCID 0000-0002-0052-8660
Emma BadowskiUniversity of Western Ontario, Roth McFarlane Hand & Upper Limb Centre, St Joseph's Health Care, London, Ontario, Canada.
Matan J CohenClalit Health Services, Affiliated with the Hebrew University Faculty of Medicine, Jerusalem District, Jerusalem, Israel.
G Daniel G LangohrUniversity of Western Ontario, Roth McFarlane Hand & Upper Limb Centre, St Joseph's Health Care, London, Ontario, Canada.
Assaf KadarUniversity of Western Ontario, Roth McFarlane Hand & Upper Limb Centre, St Joseph's Health Care, London, Ontario, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: De Quervain's tenosynovitis (DQT), marked by pain and dysfunction from thickening of the first dorsal compartment, traditionally relies on treatments like corticosteroid injections, physiotherapy, braces, and surgery. This study explores hyaluronic acid (HA), recognized for its lubricating properties, as a nonsurgical alternative to improve tendon gliding at the tendon-retinaculum interface. Study Design: Biomechanical cadaveric study. Materials and Methods: Eighteen cadaveric specimens of the first extensor tendon compartment were soaked in saline. Half were treated with HA and half with celestone soluspan. Friction between the abductor pollicis longus (APL) and extensor pollicis brevis (EPB) tendons against the extensor retinaculum was measured at wrist-thumb angles of 30 to 20 degrees and 30 to 0 degrees. Results: HA significantly reduced friction by 18.7% compared with saline, with the greatest reduction observed in the EPB at the 30 to 20-degree angle. Conclusion: These findings indicate that HA may offer a promising nonsurgical treatment for DQT and support further clinical trials.

Indexed as

biomechanicalcorticosteroidDe Quervain's tenosynovitisextensor tendonsfriction testinggliding resistancehand surgeryhyaluronic acid

Identifiers

PMID41869473
PMCPMC13002296

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.