Evidence map›Paper›PMID 41869352›Full record

ArticleFrontiers in immunology2026

The species, distribution, resistance of donor-derived pathogens and their impact on solid organ transplant recipients.

Yan-Man Zhou, Xian-Quan Cui, Peng Zhao, Zhi-Guo Peng, Ning Guo, Huai-Bin Sun, Sheng-Li Liu

Abstract read
In one paragraph

Article in Frontiers in immunology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Yan-Man ZhouDepartment of Nephrology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, Shandong, China.
Xian-Quan CuiDepartment of Organ Transplantation, Qilu Hospital of Shandong University, Jinan, Shandong, China.
Peng ZhaoDepartment of Organ Transplantation, Qilu Hospital of Shandong University, Jinan, Shandong, China.
Zhi-Guo PengDepartment of Organ Transplantation, Qilu Hospital of Shandong University, Jinan, Shandong, China.
Ning GuoDepartment of Organ Transplantation, Qilu Hospital of Shandong University, Jinan, Shandong, China.
Huai-Bin SunDepartment of Organ Transplantation, Qilu Hospital of Shandong University, Jinan, Shandong, China.
Sheng-Li LiuDepartment of Organ Transplantation, Qilu Hospital of Shandong University, Jinan, Shandong, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Donor-derived infections (DDIs) have become a significant cause of infection in organ transplant recipients. Elaborating on the species, distribution, and resistance of donor-derived pathogens (DDPs) holds important implications. Methods: A retrospective cohort study included 302 deceased donors and their corresponding 464 kidney transplant recipients and 175 liver transplant recipients. We detected DDPs in preservation fluid (PF) using both conventional culture and mNGS, and subsequently analyzed the incidence of DDIs after transplantation. Results: 89.4% (270/302) of donors had positive cultures. Predominant multidrug-resistant organism included HLAR- Conclusions: Multidrug-resistant organism are prevalent in deceased donors, with PF contamination primarily originating from donors. Integration of mNGS into donor screening protocols enables timely antimicrobial intervention, potentially improving transplant outcomes.

Indexed as

BacteriaBacterial InfectionsKidney TransplantationLiver TransplantationOrgan TransplantationTissue DonorsAdultDrug Resistance, Multiple, BacterialFemaleHumansIncidenceMaleMiddle AgedRetrospective StudiesTransplant Recipientsdonor-derived infectionmetagenomic next-generation sequencingmultidrug-resistant organismpreservation fluidsolid organ transplantation

Identifiers

PMID41869352
PMCPMC13002418

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.