Evidence map›Paper›PMID 41869252›Full record

ReviewCureus2026

Comparative Evaluation of Oral Health Status in Patients Undergoing Orthodontic Treatment With Clear Aligner Therapy Versus Conventional Fixed Appliance Therapy: An Umbrella Review.

Hemannthee Thota, Himaja Vanteddu, Hepsi Singavarapu, Hepsiba A, Pushpika Sunkara, Chaitanya Krishna Dev Pillutla

Abstract readReview
In one paragraph

Review in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Hemannthee ThotaOrthodontics and Dentofacial Orthopaedics, Sibar Institute of Dental Sciences, Guntur, IND.
Himaja VantedduCollege of Dentistry, Sibar Institute of Dental Sciences, Guntur, IND.
Hepsi SingavarapuOrthodontics and Dentofacial Orthopaedics, Drs. Sudha and Nageswara Rao Siddhartha Institute of Dental Sciences, Vijayawada, IND.
Hepsiba AOrthodontics and Dentofacial Orthopaedics, Gitam Dental College, Visakhapatnam, IND.
Pushpika SunkaraOrthodontics and Dentofacial Orthopaedics, Drs. Sudha and Nageswara Rao Siddhartha Institute of Dental Sciences, Vijayawada, IND.
Chaitanya Krishna Dev PillutlaOrthodontics and Dentofacial Orthopaedics, Sibar Institute of Dental Sciences, Guntur, IND.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Orthodontic treatment serves an essential function in correcting malocclusion and improving both function and esthetics, but different appliance systems can influence oral health outcomes due to variations in plaque accumulation, gingival response, and enamel demineralization. Clear aligner therapy (CAT) has gained recognition as a substitute for traditional fixed appliance therapy (CFAT), asserting advantages such as improved oral hygiene and fewer periodontal issues. This overview assesses and integrates results from current systematic reviews and meta-analyses that compare the oral health conditions of patients receiving CAT with those treated with CFAT. An extensive examination of peer-reviewed Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines-compliant meta-analyses and systematic reviews was carried out, making use of databases like PubMed, Scopus, and the Cochrane Library. Studies assessing oral hygiene parameters, including periodontal, gingival, and plaque indices, and enamel demineralization, were included. The reviews chosen were assessed based on their methodological rigor, founded on the AMSTAR-2 criteria. After eliminating 327 duplicates, there were 916 records left for title and abstract screening. Out of these, 742 records were discarded for failing to fulfill the inclusion requirements. The entire texts of 174 articles were evaluated for inclusion, with 166 being excluded because there were insufficient data, irrelevant outcomes, or poor study design. In the end, the inclusion criteria were fulfilled by eight meta-analyses and systematic reviews, which were incorporated into this overview. Across the included reviews, findings consistently showed superior oral hygiene results in individuals receiving treatment with clear aligners. Individuals using CAT exhibited significantly lower plaque and gingival indices in contrast to individuals who received fixed appliances, largely due to the removability of aligners, which enables more efficient oral hygiene practices. However, evidence regarding long-term periodontal effects and enamel demineralization remains limited and heterogeneous. Most reviews demonstrated moderate methodological quality and highlighted the necessity for uniform outcome metrics and extended follow-up durations. Typically, current research indicates that clear aligner therapy provides better short-term oral health outcomes than conventional fixed appliances. Despite these promising findings, variations in study design and a lack of long-term data underscore the necessity for further high-quality research to draw definitive conclusions about long-term oral health relating to periodontal conditions and the risk of cavities.

Indexed as

clear alignersclear aligner therapyconventional fixed appliance therapyfixed orthodontic appliancesgingival healthmeta-analysisoral healthplaque-indexsystematic review

Identifiers

PMID41869252
PMCPMC12999544

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.