ArticleCureus2026
Pseudoendocrine Sarcoma: Unusual Manifestation in the Lower Leg.
Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Pseudoendocrine sarcoma is a recently described rare soft tissue neoplasm. The tumor predominantly affects older adults, with the paravertebral soft tissue as a predilection site. We report on an unusual location of pseudoendocrine sarcoma in the right gastrocnemius muscle of a 59-year-old male patient. Histology showed a remarkable neuroendocrine-like morphology. Immunohistochemically, the tumor cells were negative for chromogranin, synaptophysin, and INSM-1 but positive for beta-catenin, CD56, and multifocally for S100. By molecular analysis, an S37F point mutation in exon 3 of the CTNNB1 gene was detected. This case, to our knowledge, illustrates a hitherto unreported location of a pseudoendocrine sarcoma in the lower leg. The relevant differential diagnoses are discussed with special regard to CD56 and S100.
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