ArticleCureus2026
Gastric Mucosal Biopsy Revealing Immunoglobulin G4 (IgG4)-Related Disease With Subtle Macroscopic Changes: A Case Report.
Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Immunoglobulin G4 (IgG4)-related disease affects multiple organs throughout the body, including the pancreas, bile ducts, lacrimal glands, salivary glands, lungs, kidneys, retroperitoneum, and lymph nodes; however, reports of gastrointestinal involvement are scarce. We report the case of a 40-year-old Japanese woman who presented with bilateral eyelid edema and enlargement of the submandibular and parotid glands. Upper gastrointestinal endoscopy was performed due to epigastric discomfort. Although the endoscopy revealed minimal mucosal abnormalities, the gastric mucosal biopsy demonstrated marked IgG4-positive plasma cell infiltration. These findings provided sufficient pathological evidence to establish a diagnosis of IgG4‑related disease. The patient was treated with steroid therapy, which was highly effective and resulted in rapid symptom improvement. This case highlights that in patients with gastrointestinal symptoms, a gastric mucosal biopsy is valuable for the definitive diagnosis of IgG4-related disease, even when gross endoscopic findings are limited.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.