Evidence map›Paper›PMID 41869238›Full record

ArticleCureus2026

Radiotherapy in the Treatment of Unresectable Recurrent Tracheal Pleomorphic Adenoma: A Case Report and Review of the Literature.

Sara Harbaj, Amina Majdi, Boutaina Agdi, Rania Chakir, Amine Lachgar, Karima Nouni, Hanan El Kacemi, Tayeb Kebdani, Khalid Hassouni

Abstract readCase Reports
In one paragraph

Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Sara HarbajDepartment of Radiotherapy, National Institute of Oncology, Faculty of Medicine and Pharmacy - University Mohammed V, Rabat, MAR.
Amina MajdiDepartment of Radiotherapy, National Institute of Oncology, Faculty of Medicine and Pharmacy - University Mohammed V, Rabat, MAR.
Boutaina AgdiDepartment of Radiotherapy, National Institute of Oncology, Faculty of Medicine and Pharmacy - University Mohammed V, Rabat, MAR.
Rania ChakirDepartment of Radiotherapy, National Institute of Oncology, Faculty of Medicine and Pharmacy - University Mohammed V, Rabat, MAR.
Amine LachgarDepartment of Radiotherapy, National Institute of Oncology, Faculty of Medicine and Pharmacy - University Mohammed V, Rabat, MAR.
Karima NouniDepartment of Radiotherapy, National Institute of Oncology, Faculty of Medicine and Pharmacy - University Mohammed V, Rabat, MAR.
Hanan El KacemiDepartment of Radiotherapy, National Institute of Oncology, Faculty of Medicine and Pharmacy - University Mohammed V, Rabat, MAR.
Tayeb KebdaniDepartment of Radiotherapy, National Institute of Oncology, Faculty of Medicine and Pharmacy - University Mohammed V, Rabat, MAR.
Khalid HassouniDepartment of Radiotherapy, National Institute of Oncology, Faculty of Medicine and Pharmacy - University Mohammed V, Rabat, MAR.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pleomorphic adenoma of the trachea is a rare tumor, with fewer than 50 cases reported. Its nonspecific symptoms can delay diagnosis. We describe the case of a 48-year-old woman with recurrent obstructive pleomorphic adenoma of the trachea. She was initially treated with endoscopic resection in 2019. In 2024, she developed increasing respiratory distress due to an inoperable recurrence. The patient received volumetric modulated arc therapy (VMAT) with a dose of 20 Gy in five treatments of 4 Gy each. This provided rapid symptom relief, and significant regression was observed on radiological imaging at three and 12 months. Although complete surgical removal remains the best option, this case shows that radiation therapy can be an effective choice for inoperable or recurrent tumors. The positive clinical and radiological results we observed underscore the role of radiotherapy in achieving durable local control and symptom relief. This highlights the need for thorough evaluation by multiple specialists and long-term follow-up.

Indexed as

inoperable tumormultidisciplinary managementpleomorphic adenomarecurrencetracheavmat

Identifiers

PMID41869238
PMCPMC13002232

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.