ArticleCureus2026
Temporalis Muscle Thickness as a Prognostic Factor for 30-Day, 90-Day, and Overall Mortality in Newly Diagnosed Glioblastoma.
Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
1 citing paper in PubMed.
Corrections and comments
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Authors and funding
16 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundGlioblastoma (GBM) is the most common primary malignant brain tumor in adults. Accurate prognostic biomarkers are needed to guide care and treatment pathways across the spectrum of age. Temporal muscle thickness (TMT) is an accessible parameter that has been recognized as a prognostic marker for GBM. In addition, frailty, as measured by sarcopenia, has been proven to predict overall survival in other oncologic processes.
objectiveWe evaluated whether sarcopenia, as measured by temporalis muscle thickness, has prognostic value for predicting survival in GBM. We aimed to confirm its prognostic accuracy and compare it to other survival markers.
methodsA prospective GBM database identified 257 patients undergoing initial diagnostic surgery at Henry Ford Hospital in Detroit, Michigan. Sarcopenia was quantified by temporalis muscle thickness and grouped into tertiles. Mortality hazard ratios were calculated using multivariate analysis.
resultsAfter multivariate analysis, sarcopenia at the time of initial surgery was the only factor associated with mortality at 30 days postoperatively (OR 0.10,
conclusionsSarcopenia has prognostic value for predicting postoperative 30-day, 90--day, and overall survival from diagnosis in GBM. The frailty/sarcopenia paradigm is independent of patient demographic, oncologic, genetic, surgical, and therapeutic factors. Temporalis muscle thickness assessment provides a simple method to help guide treatment decisions in affected adult populations.
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