Evidence map›Paper›PMID 41869130›Full record

ArticleCureus2026

Poly-Infections in a Patient Living With Human Immunodeficiency Virus (HIV).

Annarose M Sorvillo, Vadim Belinschi, Camille Akkari, Jihad Slim, Madeline G Ciccone

Abstract readCase Reports
In one paragraph

Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Annarose M SorvilloPharmaceutical Education, Fairleigh Dickinson University College of Pharmacy and Health Sciences, Florham Park, USA.
Vadim BelinschiInfectious Diseases, Saint Michael's Medical Center, Newark, USA.
Camille AkkariInternal Medicine, Saint Michael's Medical Center, Newark, USA.
Jihad SlimInfectious Diseases, Saint Michael's Medical Center, Newark, USA.
Madeline G CicconeInfectious Diseases, Saint Michael's Medical Center, Newark, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Febrile neutropenia (FN) is a medical emergency typically seen in immunocompromised patients with neutrophil counts below 500 cells/µL. It is often associated with chemotherapy, hematologic malignancy, and advanced human immunodeficiency virus (HIV) infection. Severe neutropenia in a low-level viremia and preserved CD4 T-helper cell (CD4) is uncommon and warrants evaluation for alternative etiologies. A 68-year-old man with HIV presented with fever and an absolute neutrophil count (ANC) of zero, without recent chemotherapy or other known myelosuppressive medications. Gram-negative bacteremia was identified, which is often attributed to gut translocation in neutropenic patients. Despite early initiation of tbo-filgrastim, the neutrophil count failed to respond; thus, a bone marrow biopsy was done to evaluate for an underlying marrow disorder. Bone marrow examination combined with genetic and molecular testing revealed a diagnosis of T-cell large granular lymphocytic leukemia (T-LGL), which explained the lack of response to tbo-filgrastim. Because the patient presented with profound neutropenia, gram-negative bacteremia, and a concern of hematologic malignancy,

Indexed as

candida esophagitishematologic malignancyhivimmunocompromisedneutropeniastrongyloides

Identifiers

PMID41869130
PMCPMC13003700

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.