ArticleLancet regional health. Americas2026
Surgical outcomes and quality of life in octogenarians with early-stage non-small cell lung cancer: a prospective cohort study.
Article in Lancet regional health. Americas, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Major Postoperative Complications and Survival After Lung Cancer Resection in Patients Aged ≥80 Years: Risk Factor Analysis.Current oncology (Toronto, Ont.) · 2026Article
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Authors and funding
19 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: As life expectancy increases, more adults aged ≥80 years are diagnosed with early-stage lung cancer. Often these patients are excluded from screening programs and clinical trials due to concerns about comorbidities and surgical risk as evidence on surgical outcomes and quality of life (QoL) remains limited. We aimed to compare postoperative outcomes, survival, and QoL between octogenarians and younger patients undergoing surgery for Stage IA NSCLC. Methods: We included patients with stage IA non-small cell lung cancer from the Mount Sinai Health System enrolled in the prospective Initiative for Early Lung Cancer Research on Treatment (IELCART) study. Octogenarians (80 years and older) were compared to younger patients in terms of clinical presentation, type of surgery, postoperative outcomes, and survival. Quality of life was assessed using physical and mental health scores at baseline and at 1, 6, and 12 months after surgery. Lung cancer-specific and overall survival were analyzed using Kaplan-Meier methods. Findings: Among 884 patients, 114 (12.9%) were octogenarians. Compared to 770 younger patients, octogenarians had similar comorbidities but underwent more frequently sublobar resections [90/114 (78.9%) vs. 485/770 (62.4%), Interpretation: Among octogenarians with early-stage NSCLC, surgical treatment was associated with favorable safety and long-term quality-of-life outcomes in carefully selected patients. Funding: This study was supported by generous grants from the Simons Foundation (International, Ltd.).
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