ArticleAmerican journal of translational research2026
Percutaneous mechanical thrombectomy combined with catheter-directed thrombolysis improves clinical outcomes in subacute lower extremity deep vein thrombosis.
Article in American journal of translational research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
objectiveTo explore the clinical efficacy of percutaneous mechanical thrombectomy (PMT) combined with catheter-directed thrombolysis (CDT) for subacute lower extremity deep vein thrombosis (DVT).
methodsA retrospective analysis was conducted on 93 patients with subacute lower extremity DVT, divided into the CDT group (n=45) and combined group (PMT + CDT, n=48) by treatment regimen. Clinical efficacy, thrombus clearance, related indicators and safety were compared between the two groups.
resultsThe total effective rate of the combined group (97.92%) was significantly higher than that of the CDT group (82.22%) (P<0.05), with superior thrombus removal grade, significantly shorter thrombolysis duration, lower drug dosage and shorter hospital stay (all P<0.05). After treatment, the combined group showed more significant improvements in coagulation, inflammation, limb circumference difference and hemorheology indexes, with a lower recurrence rate (4.17% vs 17.78%, P<0.05). There was no significant difference in complication rate between the two groups (P>0.05).
conclusionPMT combined with CDT exerts significant efficacy and favorable safety in treating subacute lower extremity DVT, and can reduce recurrence risk.
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