Evidence map›Paper›PMID 41868763›Full record

ReviewJournal of the Society for Cardiovascular Angiography & Interventions2026

Long Femoropopliteal Lesions Challenge the Limits of Endovascular Technique: Contemporary Systematic Review and Meta-analysis.

Sameh Sayfo, Anne M Ryschon, Ami Sood, Abigail M Garner, Peter A Soukas, Prakash Krishnan, Jan B Pietzsch, Peter A Schneider

Abstract readReview
In one paragraph

Review in Journal of the Society for Cardiovascular Angiography & Interventions, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Sameh SayfoDepartment of Interventional Cardiology, Baylor Scott & White The Heart Hospital - Plano, Plano, Texas.
Anne M RyschonWing Tech Inc., Menlo Park, California.
Ami SoodEndologix, Campbell, California.
Abigail M GarnerWing Tech Inc., Menlo Park, California.
Peter A SoukasBrown University Health Cardiovascular Institute, Providence, Rhode Island.
Prakash KrishnanThe Zena and Michael A Wiener Cardiovascular Institute, Icahn School of Medicine at Mount Sinai, New York, New York.
Jan B PietzschWing Tech Inc., Menlo Park, California.
Peter A SchneiderDepartment of Surgery, University of California, San Francisco, San Francisco, California.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Traditionally, patients with symptomatic femoropopliteal artery occlusive disease have been treated surgically. However, a growing body of clinical evidence has emerged supporting endovascular treatment in patients with long lesions. The objective of this systematic search and meta-analysis was to assess contemporary outcomes in patients undergoing endovascular treatment for long femoral-popliteal lesions. Methods: An updated systematic search of Embase, including MEDLINE, identified relevant records published between January 2000 and March 2023 reporting a minimum of 1-year follow-up of endovascular revascularization in patients with mean lesion length ≥20 cm. A pooled meta-analysis was performed using a random-effects model for all longitudinal cumulative event rates. Subgroup analyses explored stratification by lesion length, intervention, study design, and outcome definition. Quality of evidence and risk of bias assessments were conducted. Results: A total of 28 records, 2338 limbs, and 2311 patients, were analyzed. The pooled cumulative event rates (95% CI) for primary patency were as follows: 0.85 (95% CI, 0.81-0.89), 0.67 (95% CI, 0.61-0.73), 0.48 (95% CI, 0.38-0.57), and 0.42 (95% CI, 0.33-0.52); secondary patency: 0.90 (95% CI, 0.85-0.93), 0.84 (95% CI, 0.77-0.89), 0.72 (95% CI, 0.64-0.78), 0.63 (95% CI, 0.52-0.73); and freedom from target lesion revascularization: 0.93 (95% CI, 0.89-0.96), 0.79 (95% CI, 0.74-0.83), 0.68 (95% CI, 0.62-0.73), and 0.63 (95% CI, 0.57-0.69) at 6, 12, 24, and 36 months, respectively. Select subgroup analyses showed clinically relevant variation in event rates. Conclusions: This systematic search and meta-analysis provides important insight into the performance of endovascular revascularization in patients with long lesions. These findings will need to be considered as treatment decisions are made.

Indexed as

endovascularlong lesionsmeta-analysisrevascularizationsystematic searchTASC D

Identifiers

PMID41868763
PMCPMC13005401

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.