ArticleJournal of the Society for Cardiovascular Angiography & Interventions2026
Lipid Goal Achievement With Statins Among Statin-Naïve Indian Patients Undergoing Percutaneous Coronary Intervention.
Article in Journal of the Society for Cardiovascular Angiography & Interventions, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: The effectiveness of current statin therapy in achieving lipid targets in Indian patients remains uncertain. This observational study aimed to evaluate lipid goal attainment at 1 and 6 months with atorvastatin and rosuvastatin in statin-naïve South Indian patients undergoing percutaneous coronary intervention (PCI). Methods: This prospective, observational, single-center study included 491 statin-naïve patients who underwent PCI between March 2021 and May 2023. Effects of statins on low-density lipoprotein cholesterol (LDL-C) reduction and lipid goal achievement were assessed at 1 and 6 months. Secondary objectives compared the individual efficacy of atorvastatin vs rosuvastatin, the impact of baseline lipids, statin switching, and the association between lipid goal achievement and major adverse cardiovascular events. Results: Among 491 patients (mean age, 58.7 years), 437 (89%) presented with acute coronary syndrome. Atorvastatin was prescribed to 327 (66%) and rosuvastatin to 164 (34%). Baseline LDL-C was lower in the rosuvastatin group (122.7 ± 46.2 vs 138.2 ± 48.5 mg/dL; Conclusions: Only 41.1% and 42.5% of statin-naïve Indian patients undergoing PCI achieved lipid goals on statins at 1 and 6 months, suggesting a need for more intensive lipid-lowering strategies post-PCI. Rosuvastatin was marginally more efficacious than atorvastatin.
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