Evidence map›Paper›PMID 41868688›Full record

ReviewAmerican journal of nuclear medicine and molecular imaging2026

Theranostic applications of CXCR4-targeted imaging ligands in lymphoma: integrating diagnosis and precision therapy.

Karena R Dhamecha, Owen C Booth, Oluwaseyi M Oderinde, Qi-Huang Zheng

Abstract readReview
In one paragraph

Review in American journal of nuclear medicine and molecular imaging, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Karena R DhamechaDepartment of Radiology and Imaging Sciences, Indiana University School of Medicine Indianapolis, IN, USA.
Owen C BoothDepartment of Radiology and Imaging Sciences, Indiana University School of Medicine Indianapolis, IN, USA.
Oluwaseyi M OderindeDepartment of Radiation Oncology, Indiana University School of Medicine Indianapolis, IN, USA.
Qi-Huang ZhengDepartment of Radiology and Imaging Sciences, Indiana University School of Medicine Indianapolis, IN, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

C-X-C chemokine receptor 4 (CXCR4) is a G protein-coupled receptor implicated in immune regulation, tumor progression, and therapy resistance. In lymphoma, CXCR4 overexpression promotes malignant cell survival via microenvironmental retention and activation of pro-survival pathways, correlating with poor prognosis. Its extracellular localization makes it a strong candidate for selective molecular imaging and targeted therapy. This review summarizes recent advances in CXCR4-targeted agents for lymphoma. Peptide-based radiotracers (

Indexed as

C-X-C chemokine receptor 4 (CXCR4)lymphomamolecular imagingpositron emission tomography (PET)single photon emission computed tomography (SPECT)theranostics

Identifiers

PMID41868688
PMCPMC13003231

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.