Evidence map›Paper›PMID 41868600›Full record

ArticleExperimental biology and medicine (Maywood, N.J.)2026

Metabolomics-guided identification of bioactive phytometabolites from South African plants targeting neuroblastoma.

Mmei Cheryl Motshudi, Clarissa Marcelle Naidoo, Chikwelu Lawrence Obi, Benson Chucks Iweriebor, Earl Prinsloo, Muhammad Sulaiman Zubair, Nqobile Monate Mkolo

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Experimental biology and medicine (Maywood, N.J.), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Mmei Cheryl MotshudiDepartment of Biology, School of Science and Technology, Sefako Makgatho Health Science University, Pretoria, South Africa.
Clarissa Marcelle NaidooDepartment of Biology, School of Science and Technology, Sefako Makgatho Health Science University, Pretoria, South Africa.
Chikwelu Lawrence ObiDepartment of Biology, School of Science and Technology, Sefako Makgatho Health Science University, Pretoria, South Africa.
Benson Chucks IwerieborDepartment of Biology, School of Science and Technology, Sefako Makgatho Health Science University, Pretoria, South Africa.
Earl PrinslooDepartment of Biotechnology, Rhodes University, Makhanda, South Africa.
Muhammad Sulaiman ZubairDepartment of Pharmacy, University of Tadulako, Palu, Indonesia.
Nqobile Monate MkoloDepartment of Biology, School of Science and Technology, Sefako Makgatho Health Science University, Pretoria, South Africa.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Neuroblastoma constitutes a solid tumor in pediatric populations, characterized by a dismal prognosis and a scarcity of effective therapeutic interventions. Medicinal flora from South Africa represents valuable sources of bioactive phytometabolites with potential relevance to neuroblastoma. This study employed an integrated workflow merging untargeted UPLC-MS/MS metabolomics, mitochondrial functional assays, and

Indexed as

AcorusAntineoplastic Agents, PhytogenicLippiaMetabolomicsNeuroblastomaPlant ExtractsCell Line, TumorCell SurvivalChromatography, High Pressure LiquidHumansMembrane Potential, MitochondrialSouth AfricaTandem Mass SpectrometryAntineoplastic Agents, PhytogenicPlant ExtractsAcorus calamusADMELippia javanicametabolomicsmitochondrial membrane potential

Identifiers

PMID41868600
PMCPMC13001226

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.