Trial reportFrontiers in neurology
Comparative effects of resistance- and assistance-based robot training on brain activation and motor recovery in stroke patients.
Trial report in Frontiers in neurology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
2 authors.
Funding
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Abstract
Background: Stroke is a significant cause of disability worldwide, often resulting in persistent upper-limb dysfunction. Robot-assisted therapy has emerged as an effective rehabilitation strategy by enabling intensive, repetitive, and task-specific training. In this study, we aimed to investigate the effects of resistance- versus assistance-based robotic interventions on brain activation and motor recovery in patients with stroke, as these effects remain insufficiently understood. Methods: Twenty-five adults with hemiparetic stroke were randomized to a resistance-based robot training group (RTG, Results: Prefrontal activation decreased from pre- to post-intervention in both groups. In the ipsilesional hemispheres, differences between groups were significant ( Conclusion: Resistance-based robotic training was associated with greater motor improvements in kinematic smoothness, and larger reductions in prefrontal activation within ipsilesional hemispheres compared with assistance-based training. These findings suggest differences in prefrontal activation patterns accompanied by improvements in kinematic movement smoothness in stroke survivors. Clinical trial registration: https://cris.nih.go.kr, (Registration Number: KCT0011076).
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