ArticleAmerican heart journal plus : cardiology research and practice2026
Mortality trends related to cardiovascular disease subtypes among adult females in the United States, 2010-2023.
Article in American heart journal plus : cardiology research and practice, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Cardiovascular disease (CVD) is the leading cause of death among females in the US, but recent shifts in subtype-specific mortality patterns need closer examination. This study aimed to evaluate trends in CVD-related mortality and its major subtypes among adult females from 2010 to 2023. Method: This study used CDC WONDER multiple cause of death data for CVD and its subtypes for adult females aged ≥25. Age-adjusted mortality rates (AAMR) per 100,000 with 95% confidence intervals were reported. Temporal trends from 2010 to 2019 were analyzed using Joinpoint Regression Software to estimate the average annual percent change (AAPC). Data from 2020 to 2023 were reported descriptively and excluded from trend analysis. Results: Between 2010 and 2023, 10,642,363 CVD-related deaths were reported. The overall CVD-related AAMR was higher in 2023 (535.4) than in 2010 (526.1). The AAMR decreased significantly from 2010 to 2019 (AAPC: -0.60), followed by a sharp rise in 2020 (570.8) and 2021 (604.5), and a subsequent decline in 2022 (559.1) and 2023 (535.4). Hypertensive diseases, heart failure/cardiomyopathy, and pulmonary heart diseases reported an increase in AAMR from 2010 to 2019, while ischemic heart diseases, cerebrovascular heart diseases, and valvular heart diseases reported a decrease. Nearly all subtypes reported marked increases during the peak pandemic years, followed by a partial recovery in 2022 and 2023. Conclusion: CVD-related mortality among adult females showed a decline before 2020 but rose sharply during the pandemic. Post-pandemic recovery strategies should prioritize targeted interventions for key CVD subtypes and resilience in cardiovascular care for females.
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