ArticleFrontiers in medicine2026
Association between fundus tessellated density and subfoveal choroidal thickness in children with different refractive statuses.
Article in Frontiers in medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Artificial intelligence-quantified fundus tessellated density and its association with myopia severity in Chinese children: a cross-sectional study.Frontiers in cell and developmental biology · 2026Article
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective: Present study aimed to quantitatively evaluate the association between fundus tessellated density (FTD) and subfoveal choroidal thickness (SFCT) in children with different refractive statuses and to explore the potential of FTD as a non-invasive biomarker for monitoring myopic progression. Methods: A cross-sectional study was conducted involving 619 eyes of 315 children aged 6-12 years. Participants were classified into four refractive groups: hyperopia, pre-myopia, low myopia, and moderate-to-high myopia. FTD was quantitatively assessed using artificial intelligence (AI)-based analysis of color fundus photographs. SFCT and central subfield thickness (CST) were measured using swept-source optical coherence tomography (SS-OCT). Correlation and threshold effect analyses were performed to examine the relationship between FTD and SFCT. Results: SFCT decreased significantly with increasing myopic severity ( Conclusion: FTD and SFCT are significantly associated in a nonlinear manner in myopic children, with a defined threshold effect that varies by refractive status. AI-based FTD measurement offers a reproducible and accessible method for quantifying early structural changes in myopia. The identified nonlinear relationship and threshold suggest that combined assessment of FTD and SFCT may hold promise for improving early detection and monitoring of pediatric myopic progression, warranting further longitudinal validation.
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