ArticleFrontiers in medicine2026
Remnant cholesterol: a risk stratification aid for coronary artery stenosis severity in patients with type 2 diabetes.
Article in Frontiers in medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Objective: To investigate the association between remnant cholesterol (RC) levels and the degree of coronary artery stenosis in patients with type 2 diabetes, and to assess its incremental value in risk stratification. Methods: A retrospective study was conducted on 155 patients with type 2 diabetes diagnosed and treated in the Department of Cardiology at Zhaotong Third People's Hospital from January 2023 to December 2024. Based on coronary angiography Gensini scores, patients were divided into a mild stenosis group (Gensini < 22 points) and a moderate-to-severe stenosis group (Gensini ≥ 22 points). Clinical characteristics were compared between the two groups. Spearman's correlation analysis assessed the relationship between RC and Gensini scores. Logistic regression analyzed the association between RC and coronary artery stenosis severity. ROC curves evaluated the diagnostic capability of RC, while NRI and IDI measures assessed its incremental diagnostic value. Results: The RC in the moderate-to-severe stenosis group was higher than that in the mild stenosis group ( Conclusion: Levels of RC in patients with type 2 diabetes are independently associated with the degree of coronary artery stenosis. Beyond traditional risk factors, RC demonstrates clear incremental value and can serve as an auxiliary indicator for stratifying the risk of coronary artery stenosis.
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