Evidence map›Paper›PMID 41868232›Full record

ArticleFrontiers in medicine2026

Negative association of hemoglobin levels with mortality in older Japanese patients with dysphagia: a retrospective cohort study.

Ya-Ting Yuan, Miao Wang, Xian-Zhi Liu, Xiao Cheng, Xue-Ying Cai, Han-Han Chen, Xiao-Bin Zhang

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Article in Frontiers in medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Ya-Ting Yuan *Department of Pulmonary and Critical Care Medicine, Zhongshan Hospital Xiamen University, School of Medicine, Xiamen University, Xiamen, Fujian, China.
Miao Wang *Department of Pulmonary and Critical Care Medicine, Zhongshan Hospital Xiamen University, School of Medicine, Xiamen University, Xiamen, Fujian, China.
Xian-Zhi Liu *Xiang'an Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen, Fujian, China.
Xiao Cheng *Department of Pulmonary and Critical Care Medicine, Zhongshan Hospital Xiamen University, School of Medicine, Xiamen University, Xiamen, Fujian, China.
Xue-Ying Cai *Department of Pulmonary and Critical Care Medicine, Zhongshan Hospital Xiamen University, School of Medicine, Xiamen University, Xiamen, Fujian, China.
Han-Han Chen *Department of Pulmonary and Critical Care Medicine, Zhongshan Hospital Xiamen University, School of Medicine, Xiamen University, Xiamen, Fujian, China.
Xiao-Bin ZhangDepartment of Pulmonary and Critical Care Medicine, Zhongshan Hospital Xiamen University, School of Medicine, Xiamen University, Xiamen, Fujian, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: This secondary analysis aimed to examine the association between hemoglobin levels and mortality in older Japanese individuals with dysphagia. Methods: Data from 253 patients with clinically confirmed dysphagia between January 2014 and January 2017 were analyzed. Participants were divided into three tertiles based on their hemoglobin levels (T1: 5.4-10.2 g/dL; T2: 10.2-12.0 g/dL; T3: ≥12.0 g/dL). Cox proportional hazards regression was used to evaluate mortality risk, supplemented by Kaplan-Meier survival analysis and subgroup interaction assessments. Results: The study included 154 female and 99 male patients, with a median age of 83 years. The cohort demonstrated a significant inverse relationship between hemoglobin levels and mortality. After full covariate adjustment, each 1 g/dL increase in hemoglobin level corresponded to a 14% mortality risk reduction (HR = 0.86, 95% CI: 0.77-0.97, Conclusion: Hemoglobin concentration was independently and inversely associated with mortality in older Japanese patients with dysphagia. These findings underscore the prognostic value of hemoglobin in this population.

Indexed as

dysphagiahemoglobinmortalityolder adultsretrospective cohort study

Identifiers

PMID41868232
PMCPMC12999952

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