Evidence map›Paper›PMID 41868224›Full record

SynthesisFrontiers in medicine2026

Objective monitoring of postpartum uterine activity: a systematic scoping review.

Phebe B Q Berben, Marion W E Frenken, Annemarie F Fransen, Eugenie J L G Delvaux, Myrthe van der Ven, M Beatrijs van der Hout-van der Jagt, S Guid Oei, Judith O E H van Laar

Abstract readSystematic Review
In one paragraph

Synthesis in Frontiers in medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Phebe B Q BerbenDepartment of Obstetrics and Gynecology, Máxima Medical Center, Veldhoven, Netherlands.
Marion W E FrenkenDepartment of Obstetrics and Gynecology, Máxima Medical Center, Veldhoven, Netherlands.
Annemarie F FransenDepartment of Obstetrics and Gynecology, Zuyderland Medical Center, Sittard-Geleen, Netherlands.
Eugenie J L G DelvauxDepartment of Science and Medical Innovation, Máxima Medical Center, Veldhoven, Netherlands.
Myrthe van der VenDepartment of Obstetrics and Gynecology, Máxima Medical Center, Veldhoven, Netherlands.
M Beatrijs van der Hout-van der JagtDepartment of Obstetrics and Gynecology, Máxima Medical Center, Veldhoven, Netherlands.
S Guid OeiDepartment of Obstetrics and Gynecology, Máxima Medical Center, Veldhoven, Netherlands.
Judith O E H van LaarDepartment of Obstetrics and Gynecology, Máxima Medical Center, Veldhoven, Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To minimize risks of postpartum hemorrhage, understanding normal postpartum uterine activity is essential. This scoping review summarizes literature on postpartum uterine activity to provide insight into uterine activity (patho)physiology, characteristics of objective postpartum uterine monitoring methods and the effect of uterotonics on postpartum uterine activity. Data sources: A systematic search was conducted in PubMed, Embase and Cochrane in August 2024 and repeated in January 2025. No filter restrictions were applied. Systematic article selection was performed by two independent reviewers. Eligibility criteria: Articles were included if study participants were ≥ 18 years old and had external tocodynamometry (TOCO), intrauterine pressure catheter (IUPC) and/or electrohysterography (EHG) monitoring postpartum. Reviews, case reports, conference papers, technical modeling methods, guidelines, grey literature and duplicates were excluded, as were articles describing non-pregnant, non-human, non-labor studies and intrapartum studies. Study appraisal and synthesis methods: The Newcastle-Ottawa Quality Assessment Scale and the revised Cochrane risk-of-bias tool were conducted to assess study quality. Data was collected and systematically organized by two independent reviewers. Results: Twenty-nine articles were included after evaluation of 5,826 articles. Data analysis included 23 articles (IUPC n = 16, EHG n = 6 and TOCO n = 1) after risk of bias selection. Uterine contraction frequency without uterotonics ranges between 2.4 and 2.8 contractions per 10 min and between 3.7 and 4.6 contractions per 10 min with oxytocin, both decreasing over time. Normal baseline activity after childbirth is ≤ 15 mmHg and normal uterine intensity varies between 51-58 mmHg and 336-396 Montevideo Units. Studies conducted prior to 2020, measuring uterine activity with IUPC or TOCO, report no significant correlation between uterine activity and total blood loss. However, a small study using EHG conducted in 2024, cautiously suggests a positive relationship. This review highlights the need for a uniform and objective method to monitor postpartum uterine activity to adequately investigate the impact of different uterotonics on uterine activity. Conclusion: The (patho)physiology of postpartum uterine activity remains largely underexplored. EHG shows potential in enhancing our understanding of normal postpartum uterine activity as well as in postpartum hemorrhage recognition and prediction.

Indexed as

myometrial activitypostpartumthird stage of laboruterine contraction (MeSH)uterine monitoring (MeSH)

Identifiers

PMID41868224
PMCPMC12999783

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.