Evidence map›Paper›PMID 41868150›Full record

ArticleFrontiers in cellular and infection microbiology2026

Overexpression of AS

Yuting Sun, Han Du, Xuele Pan, Zheng Wang, Xinyi Zhang, Ruiqi Yang, Hong Chen, Deqin Yang

Abstract read
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Yuting Sun *Department of Endodontics, The Afffliated Stomatological Hospital of Chongqing Medical University, Chongqing, China.
Han Du *Department of Endodontics, The Afffliated Stomatological Hospital of Chongqing Medical University, Chongqing, China.
Xuele PanDepartment of Endodontics, The Afffliated Stomatological Hospital of Chongqing Medical University, Chongqing, China.
Zheng WangDepartment of Endodontics, The Afffliated Stomatological Hospital of Chongqing Medical University, Chongqing, China.
Xinyi ZhangDepartment of Endodontics, The Afffliated Stomatological Hospital of Chongqing Medical University, Chongqing, China.
Ruiqi YangDepartment of Endodontics, The Afffliated Stomatological Hospital of Chongqing Medical University, Chongqing, China.
Hong ChenDepartment of Endodontics, The Afffliated Stomatological Hospital of Chongqing Medical University, Chongqing, China.
Deqin YangDepartment of Endodontics, The Afffliated Stomatological Hospital of Chongqing Medical University, Chongqing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Objective: To investigate the chemical-genetic cooperative antibiofilm strategy inhibition and mechanisms of AS Methods: The minimal inhibitory concentration and minimal bactericidal concentration of DMAHDM and chlorhexidine were determined. Biofilm properties were evaluated via biomass assessment, EPS quantification, lactate production measurement, and colony-forming unit counting. Biofilm structures were examined by scanning electron microscopy. Mechanisms were investigated using RT-qPCR, zymography, and western blot. Rat caries model was employed to assess caries formation under different treatment conditions. Results: The AS Conclusion: The strategy of combining AS

Indexed as

Anti-Bacterial AgentsBacterial ProteinsDental CariesMethacrylatesStreptococcus mutansAnimalsBiofilmsGene Expression Regulation, BacterialMicrobial Sensitivity TestsPolysaccharides, BacterialQuaternary Ammonium CompoundsAnti-Bacterial AgentsBacterial Proteinsdimethylaminododecyl methacrylateMethacrylatesPolysaccharides, BacterialQuaternary Ammonium Compoundsantisense vicR (ASvicR)cariogenicitydimethylaminohexadecylmethacrylate (DMAHDM)Streptococcus mutansVicRK TCS

Identifiers

PMID41868150
PMCPMC12999838

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.