ArticleVeterinary and animal science2026
Starch Overload and Cecal Alkalinization: Impacts on the Intestinal Microbiota and Health of Horses.
Article in Veterinary and animal science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
1 citing paper in PubMed.
- A Comprehensive Review of the Equine Gut Microbiome in Health and Disease.Veterinary sciences · 2026Review
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Starch overload induces dysbiosis primarily through a reduction in cecal pH. This study aimed to evaluate the cecal microbiota following excessive starch intake, with or without the administration of an intracecal buffering solution. We hypothesized that the buffering solution would mitigate changes in the intestinal microbiota and associated clinical signs. Ten horses were randomly assigned to two groups, each receiving distinct treatments (Group I: saline solution [WSa] and starch-buffer [SB]; Group II: buffer-water [WB] and starch-saline [SSa]). Following starch overload (17.6 g/kg body weight via nasogastric tube), clinical assessments and cecal content sampling were conducted at six time points (T0, T08, T12, T24, T48, T72), corresponding to 0, 8-, 12-, 24-, 48-, and 72-hours period. DNA was extracted, and the V4 region of the 16S rRNA gene was amplified and sequenced using the Illumina platform. Sequence data were processed using QIIME2. Statistical analysis was performed using the ExpDes package in R, with means compared via Tukey's test. Diversity analysis revealed decreased richness and evenness post-treatment in Group I, with reductions observed as early as T08 in the SB treatment. The relative abundance of
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Registered trials
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