ArticleIndian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine2026
Temporal Analysis of Diastolic Shock Index in Patients with Septic Shock and Its Correlation with Clinical Outcomes in an Indian Setting: A Prospective Observational Study.
Article in Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed.
- From Descriptive Hemodynamics to Decision-grade Vasoplegia Phenotyping: The Next Translational Step for Temporal Diastolic Shock Index.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2026Article
- Author Response: From Descriptive Hemodynamics to Decision-grade Vasoplegia Phenotyping: The Next Translational Step for Temporal Diastolic Shock Index.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2026Article
- Beyond the Mean: The Dynamic Fingerprint of Vasoplegia in Septic Shock.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2026Article
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9 authors.
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Abstract
Background: Diastolic shock index (DSI), the ratio of heart rate to diastolic arterial pressure, reflects vascular tone and sympathetic drive in septic shock. While baseline DSI correlates with mortality, its temporal evolution remains exploratory. Patients and methods: In this single-center prospective observational study, adult patients with septic shock (as per sepsis-3) were enrolled. Diastolic shock index, shock index (SI), and modified shock index (MSI) were recorded at 0, 6, 12, and 24 hours. Delta diastolic shock index (ΔDSI), lactate clearance, and vasoactive-inotropic score (VIS) were analyzed using repeated-measures ANOVA, receiver operating characteristic (ROC) analysis, Cox regression, and multivariable logistic regression (SPSS v23, MedCalc). Results: Of 157 patients screened, 90 were included. Median age was 40 years (male 64.4%) with median SOFA and APACHE II scores of 9 and 18, respectively. Nonsurvivors had higher lactate (24 mg/dL, Conclusion: Temporal improvement in DSI (ΔDSI) independently predicts ICU mortality and correlates with vascular recovery. Integrating ΔDSI with VIS and lactate enhances risk stratification in septic shock. How to cite this article: Sarkar S, Sharma AK, Azim A, Chahar JS, Yadav S, Sai Saran PV,
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