Evidence map›Paper›PMID 41867936›Full record

ArticleFrontiers in pediatrics2026

Case Report: Long-term follow-up of a schoolboy with Gitelman syndrome and epilepsy-causation or coincidence?

Jiao Xue, Ying Zhang, Hongshan Zhao, Fei Li, Chengqing Yang, Zhi Yi, Kaixuan Liu, Zhenfeng Song

Abstract read
In one paragraph

Article in Frontiers in pediatrics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jiao XueDepartment of Pediatric Neurology, The Affiliated Hospital of Qingdao University, Qingdao, Shandong, China.
Ying ZhangDepartment of Pediatric Neurology, The Affiliated Hospital of Qingdao University, Qingdao, Shandong, China.
Hongshan ZhaoDepartment of Anesthesiology, The Affiliated Hospital of Qingdao University, Qingdao, Shandong, China.
Fei LiDepartment of Pediatric Neurology, The Affiliated Hospital of Qingdao University, Qingdao, Shandong, China.
Chengqing YangDepartment of Pediatric Neurology, The Affiliated Hospital of Qingdao University, Qingdao, Shandong, China.
Zhi YiDepartment of Pediatric Neurology, The Affiliated Hospital of Qingdao University, Qingdao, Shandong, China.
Kaixuan LiuDepartment of Pediatric Neurology, The Affiliated Hospital of Qingdao University, Qingdao, Shandong, China.
Zhenfeng SongDepartment of Pediatric Neurology, The Affiliated Hospital of Qingdao University, Qingdao, Shandong, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Gitelman syndrome (GS) presents with a broad range of clinical manifestations. Although uncommon, seizures secondary to severe metabolic alkalosis or hypomagnesemia have been documented. A concurrent diagnosis of epilepsy in patients with GS is even rarer. Case presentation: We report the case of a 12-year-old boy whose chief complaint was recurrent convulsions. Initial laboratory evaluation revealed normal serum magnesium levels, which subsequently decreased during follow-up. Persistent hypokalemia, hyperaldosteronism, and hypomagnesemia in subsequent disease course, as well as mutations of the Conclusion: We report a case of GS presenting with convulsions as the chief complaint. The etiology of epilepsy in this case remains unclear and may represent either a causal association or a coincidental comorbidity with GS. The mechanism of the atypical dynamics of serum magnesium levels in this patient-normal levels initially followed by a subsequent decrease-warrants further investigation.

Indexed as

epilepsyGitelman syndromehypokalemiahypomagnesemiaSLC12A3 gene

Identifiers

PMID41867936
PMCPMC12999940

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.