ReviewAmerican journal of cardiovascular disease2026
Geriatric nutritional risk index predicts all-cause mortality in patients with heart failure: an updated systematic review and meta-analysis.
Review in American journal of cardiovascular disease, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
14 authors.
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Abstract
objectivesThe role of malnutrition in heart failure (HF) patients is unclear. We assessed the correlation between the Geriatric Nutritional Risk Index (GNRI) and all-cause mortality in HF.
methodsPubMed, Scopus, and Web of Science were searched for observational studies reporting the correlation between GNRI and all-cause mortality in HF patients (up to January 26, 2025). Titles, abstracts, and full texts were screened. The Joanna Briggs Institute (JBI) Critical Appraisal Checklist was used to assess study quality. Data were synthesized via random-effects meta-analysis using the restricted maximum likelihood (REML) method. The review followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines.
resultsNineteen observational studies with 9,982 subjects were included. A low-risk GNRI group was correlated with raised all-cause mortality in HF patients (hazard ratio (HR) 1.77, 95% CI 1.38-2.16; P < 0.0001). Results were consistent across sensitivity analyses. Heterogeneity was high (I
conclusionGNRI is a reliable nutritional tool predicting all-cause mortality in HF patients. Our study suggests GNRI should be considered for evaluating long-term prognosis in this population.
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