Evidence map›Paper›PMID 41867916›Full record

ArticleAmerican journal of cardiovascular disease2026

Outcomes of Watchman device implantation in atrial fibrillation patients contraindicated for long-term anticoagulation: a single-center experience.

Ghulam Mujtaba Ghumman, Sidra Kalsoom, Fnu Salman, Anas Noman, Tarif Kanaan, Chandramohan Meenakshisundaram, Mohammed Alo, Fnu Zafrullah, Sinan Alo, Syed Sohail Ali and 1 more

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Article in American journal of cardiovascular disease, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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4 · The record

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5 · Who and what money

Authors and funding

11 authors.

Ghulam Mujtaba GhummanDepartment of Cardiology, Mercy Health Saint Vincent Medical Center Toledo, OH 43608, USA.
Sidra KalsoomDepartment of Cardiology, Mercy Health Saint Vincent Medical Center Toledo, OH 43608, USA.
Fnu SalmanDepartment of Cardiology, Mercy Health Saint Vincent Medical Center Toledo, OH 43608, USA.
Anas NomanDepartment of Cardiology, Mercy Health Saint Vincent Medical Center Toledo, OH 43608, USA.
Tarif KanaanDepartment of Cardiology, Mercy Health Saint Vincent Medical Center Toledo, OH 43608, USA.
Chandramohan MeenakshisundaramDepartment of Cardiology, Mercy Health Saint Vincent Medical Center Toledo, OH 43608, USA.
Mohammed AloDepartment of Cardiology, Mercy Health Saint Vincent Medical Center Toledo, OH 43608, USA.
Fnu ZafrullahDepartment of Cardiology, Mercy Health Saint Vincent Medical Center Toledo, OH 43608, USA.
Sinan AloDepartment of Cardiology, Mercy Health Saint Vincent Medical Center Toledo, OH 43608, USA.
Syed Sohail AliDepartment of Cardiology, Mercy Health Saint Vincent Medical Center Toledo, OH 43608, USA.
Mohammed TalebDepartment of Cardiology, Mercy Health Saint Vincent Medical Center Toledo, OH 43608, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLeft atrial appendage occlusion (LAAO) using the Watchman device is an established strategy for stroke prevention in atrial fibrillation (AF) patients at high thromboembolic risk who cannot tolerate long-term oral anticoagulation (OAC).

objectivesTo evaluate short-term clinical and echocardiographic outcomes of Watchman implantation in AF patients with contraindications to long-term OAC.

methodsWe conducted a retrospective single-center study of AF patients who underwent Watchman implantation between September 01, 2023, and March 01, 2025. Baseline demographics, comorbidities, procedural characteristics, complications, antithrombotic strategies, and 45-day outcomes were analyzed. Outcomes were compared between patients with and without follow-up TEE. Data were analyzed using SAS v9.4. All tests were two-tailed, and a

resultsAmong 10,078 AF patients, 120 underwent Watchman implantation; 105 met the inclusion criteria. The mean age was 75.8±7.8 years, and 46.7% were female. Implant success was 100%. Pericardial effusion occurred in 11 patients (10.5%, 95% CI 5.4-18.0%), including tamponade requiring pericardiocentesis in 2 patients (1.9%). Vascular access complications occurred in 3 patients (2.9%, 95% CI 0.6-8.1%). No device embolizations, device-related thrombi, or periprocedural strokes were observed. Most patients (88.5%) were discharged on dual antiplatelet therapy, while 3.8% received single antiplatelet therapy. At 45 days, 89 patients (84.8%) completed TEE; device position was stable in all. One patient (1.1%, 95% CI 0.03-6.1%) had a significant peridevice leak (>5 mm), and none had device-related thrombus. Clinical outcomes included one hemorrhagic stroke (1.1%) and eight rehospitalizations (7.6%, 95% CI 3.4-14.5%), unrelated to the device. No ischemic strokes were observed.

conclusionWatchman implantation achieved a 100% success rate with low complication rates and favorable short-term clinical and echocardiographic outcomes in AF patients contraindicated for long-term anticoagulation.

Indexed as

anticoagulation intoleranceAtrial fibrillationdual antiplatelet therapyleft atrial appendage occlusionprocedural outcomesWatchman device

Identifiers

PMID41867916
PMCPMC13003218

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