Evidence map›Paper›PMID 41867886›Full record

ArticleMachine learning: science and technology2025

CAP: Commutative algebra prediction of protein-nucleic acid binding affinities.

Mushal Zia, Faisal Suwayyid, Yuta Hozumi, JunJie Wee, Hongsong Feng, Guo-Wei Wei

Abstract read
In one paragraph

Article in Machine learning: science and technology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Mushal ZiaDepartment of Mathematics, Michigan State University, East Lansing, MI 48824, United States of America.ORCID 0000-0002-4583-5437
Faisal SuwayyidDepartment of Mathematics, Michigan State University, East Lansing, MI 48824, United States of America.ORCID 0009-0000-6677-893X
Yuta HozumiDepartment of Mathematics, Michigan State University, East Lansing, MI 48824, United States of America.ORCID 0000-0003-4674-2379
JunJie WeeDepartment of Mathematics, Michigan State University, East Lansing, MI 48824, United States of America.ORCID 0000-0001-8444-3252
Hongsong FengDepartment of Mathematics and Statistics, University of North Carolina at Charlotte, Charlotte, NC 28223, United States of America.ORCID 0000-0001-8039-3059
Guo-Wei WeiDepartment of Mathematics, Michigan State University, East Lansing, MI 48824, United States of America.ORCID 0000-0001-8132-5998

Funding

Discovery-Driven Mathematics and Artificial Intelligence for Biosciences and Drug DiscoveryR35GM148196 · NIGMS · UNIVERSITY OF GEORGIA · PI Guowei Wei · 2023 to 2026
$1.5M
NIGMS NIH HHS R35 GM148196
6 · The paper itself

Abstract

An accurate prediction of protein-nucleic acid binding affinity is vital for deciphering genomic processes, yet existing approaches often struggle in reconciling high accuracy with interpretability and computational efficiency. In this study, we introduce commutative algebra prediction (CAP) framework, which couples persistent Stanley-Reisner theory with advanced sequence embedding for predicting protein-nucleic acid binding affinities. CAP encodes proteins through transformer-learned embeddings that retain long-range evolutionary context, and represents DNA and RNA with

Indexed as

facet persistence barcodesmachine learningpersistent commutative algebrapersistent idealsprotein-nucleic acid binding

Identifiers

PMID41867886
PMCPMC13001652

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.