Evidence map›Paper›PMID 41867828›Full record

ArticlebioRxiv : the preprint server for biology2026

Preclinical validation of AAV9-TECPR2 gene therapy in a novel knock-in model of TECPR2-related disorder.

Bruna Lenfers Turnes, Peter Casey-Caplan, Leo Mejia, Tiffany Berry, Julie Zhao, Francesco Villa, Emma Cropper, Maryam Arab, Biyao Zhang, Darred Surin and 6 more

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Bruna Lenfers TurnesF.M. Kirby Neurobiology Center & Department of Neurology, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA.
Peter Casey-CaplanF.M. Kirby Neurobiology Center & Department of Neurology, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA.
Leo MejiaF.M. Kirby Neurobiology Center & Department of Neurology, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA.
Tiffany BerryF.M. Kirby Neurobiology Center & Department of Neurology, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA.
Julie ZhaoF.M. Kirby Neurobiology Center & Department of Neurology, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA.
Francesco VillaF.M. Kirby Neurobiology Center & Department of Neurology, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA.
Emma CropperF.M. Kirby Neurobiology Center & Department of Neurology, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA.
Maryam ArabHarvard Medical School, Boston, MA, USA.
Biyao ZhangF.M. Kirby Neurobiology Center & Department of Neurology, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA.
Darred SurinDepartment of Biology, Boston University, Boston, MA, USA.
Darius Ebrahimi-FakhariF.M. Kirby Neurobiology Center & Department of Neurology, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA.ORCID 0000-0002-0026-4714
Silmara de LimaDepartment of Ophthalmology, University of Pittsburg, Pittsburgh, PA, USA.
Alan S KopinTufts University School of Medicine, Boston, MA, USA.
Nick AndrewsIn Vivo Scientific Services, Salk Institute for Biological Studies, La Jolla, CA, USA.
Nathaniel HodgsonF.M. Kirby Neurobiology Center & Department of Neurology, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA.
Michela FagioliniF.M. Kirby Neurobiology Center & Department of Neurology, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA.

Funding

Genetic Analysis and Manipulation Core (GAEC)P50HD105351 · NICHD · BOSTON CHILDREN'S HOSPITAL · PI SCOTT Loren POMEROY, MUSTAFA SAHIN · 2021 to 2026
$9.4M
NICHD NIH HHS P50 HD105351
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID41867828
PMCPMC13001314

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.