Evidence map›Paper›PMID 41867798›Full record

ArticlebioRxiv : the preprint server for biology2026

Structural Basis for C

Olga A Esakova, James Jung, Hyunwook Lee, Sung Hyun Cho, John Alumasa, Erica L Schwalm, Tyler L Grove, Matthew R Bauerle, Susan L Hafenstein, Zhiheng Yu and 1 more

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Olga A EsakovaThe Department of Chemistry, The Pennsylvania State University, University Park, Pennsylvania 16802, USA.ORCID 0000-0001-8377-8368
James JungJanelia Research Campus, Howard Hughes Medical Institute, Ashburn, VA 20147, USA.ORCID 0000-0001-6830-8165
Hyunwook LeeThe Huck Institutes of the Life Sciences, The Pennsylvania State University, University Park, Pennsylvania 16802, USA.ORCID 0000-0002-5428-8594
Sung Hyun Chothe Department of Biochemistry and Biophysics (Perelman School of Medicine), University of Pennsylvania, Philadelphia, PA 19104, USA.
John AlumasaThe Department of Chemistry, The Pennsylvania State University, University Park, Pennsylvania 16802, USA.ORCID 0000-0002-9373-9618
Erica L SchwalmThe Department of Chemistry, The Pennsylvania State University, University Park, Pennsylvania 16802, USA.ORCID 0000-0002-1719-6121
Tyler L GroveThe Department of Chemistry, The Pennsylvania State University, University Park, Pennsylvania 16802, USA.
Matthew R BauerleThe Department of Chemistry, The Pennsylvania State University, University Park, Pennsylvania 16802, USA.
Susan L Hafensteinthe Department of Biochemistry and Molecular Biology, The Pennsylvania State University, University Park, Pennsylvania 16802, USA.ORCID 0000-0003-2609-4036
Zhiheng YuJanelia Research Campus, Howard Hughes Medical Institute, Ashburn, VA 20147, USA.
Squire J BookerThe Department of Chemistry, The Pennsylvania State University, University Park, Pennsylvania 16802, USA.ORCID 0000-0002-7211-5937

Funding

Radical Mechanisms of Iron-Sulfur ProteinsR35GM122595 · NIGMS · UNIVERSITY OF PENNSYLVANIA · PI SQUIRE J. BOOKER · 2017 to 2026
$3.4M
HEI: Acquisition of a Talos Arctica G2S10OD026822 · OD · PENNSYLVANIA STATE UNIVERSITY, THE · PI HAFENSTEIN, SUSAN · 2019 to 2019
$2.0M
Development of Antibiotic Adjuvants to Avert Resistance Conferred by Cfr, a Radical S-Adenosylmethionine MethylaseR21AI180902 · NIAID · UNIVERSITY OF PENNSYLVANIA · PI BOOKER, SQUIRE J. · 2024 to 2025
$437k
NIAID NIH HHS R21 AI180902NIGMS NIH HHS R35 GM122595NIH HHS S10 OD026822
6 · The paper itself

Abstract

Cfr methylates C

Identifiers

PMID41867798
PMCPMC13001441

What OpenQuestion holds

Textmetadata
LicenceCC0
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.