Evidence map›Paper›PMID 41867784›Full record

ArticlebioRxiv : the preprint server for biology2026

G-quadruplexes regulate chromatin accessibility and gene expression in Bloom Syndrome.

Dingwen Su, Veronika Altmannova, Volker Soltys, Moritz Peters, Christopher M Cunniff, John R Weir, Yingguang Frank Chan

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Dingwen SuFriedrich Miescher Laboratory of the Max Planck Society, 72076 Tübingen, Germany.ORCID 0009-0001-4909-1279
Veronika AltmannovaFriedrich Miescher Laboratory of the Max Planck Society, 72076 Tübingen, Germany.
Volker SoltysFriedrich Miescher Laboratory of the Max Planck Society, 72076 Tübingen, Germany.ORCID 0009-0008-4568-3040
Moritz PetersFriedrich Miescher Laboratory of the Max Planck Society, 72076 Tübingen, Germany.ORCID 0009-0002-6757-3834
Christopher M CunniffDepartment of Pediatrics, Weill Cornell Medical College, New York, NY, USA.ORCID 0000-0002-6041-477X
John R WeirFriedrich Miescher Laboratory of the Max Planck Society, 72076 Tübingen, Germany.ORCID 0000-0002-6904-0284
Yingguang Frank ChanFriedrich Miescher Laboratory of the Max Planck Society, 72076 Tübingen, Germany.ORCID 0000-0001-6292-9681

Funding

Clinical and Translational Science CenterUL1TR000457 · NCATS · WEILL MEDICAL COLL OF CORNELL UNIV · PI IMPERATO-MCGINLEY, JULIANNE L · 2012 to 2016
$46.0M
NCATS NIH HHS UL1 TR000457
6 · The paper itself

Abstract

Bloom Syndrome (BS) is a recessive genetic disorder characterized by hyper-recombination and genome instability. It is caused by mutations in

Identifiers

PMID41867784
PMCPMC13001512

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.