Evidence map›Paper›PMID 41867735›Full record

ArticlebioRxiv : the preprint server for biology2026

Elucidating genes sufficient for viral entry into cells through sequential genome-wide CRISPR activation screens.

Timothy Chai, Alicia Wong, Qingqing Yin, Isabel von Creytz, Jonathan S Weissman, Reuben A Saunders, Joseph B Prescott, Kyle M Loh

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Timothy ChaiInstitute for Stem Cell Biology & Regenerative Medicine, Department of Developmental Biology, Stanford University, Stanford, CA, USA.
Alicia WongInstitute for Stem Cell Biology & Regenerative Medicine, Department of Developmental Biology, Stanford University, Stanford, CA, USA.
Qingqing YinInstitute for Stem Cell Biology & Regenerative Medicine, Department of Developmental Biology, Stanford University, Stanford, CA, USA.
Isabel von CreytzCenter for Biological Threats and Special Pathogens, Robert Koch Institute, Berlin, Germany.
Jonathan S WeissmanWhitehead Institute for Biomedical Research, Department of Biology, Howard Hughes Medical Institute, Massachusetts Institute of Technology, Cambridge, MA, USA.
Reuben A SaundersWhitehead Institute for Biomedical Research, Department of Biology, Howard Hughes Medical Institute, Massachusetts Institute of Technology, Cambridge, MA, USA.
Joseph B PrescottCenter for Biological Threats and Special Pathogens, Robert Koch Institute, Berlin, Germany.
Kyle M LohInstitute for Stem Cell Biology & Regenerative Medicine, Department of Developmental Biology, Stanford University, Stanford, CA, USA.ORCID 0000-0002-8042-0149

Funding

MEDICAL SCIENTIST TRAINING PROGRAMT32GM007365 · NIGMS · STANFORD UNIVERSITY · PI CHUA, KATRIN F · 1985 to 2021
$33.8M
NIGMS NIH HHS T32 GM007365
6 · The paper itself

Abstract

A preeminent goal of virology is to discover cellular genes that mediate virus entry. Genome-wide loss-of-function screens can illuminate single genes

Identifiers

PMID41867735
PMCPMC13001310

What OpenQuestion holds

Textmetadata
LicenceCC BY-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.