Evidence map›Paper›PMID 41867722›Full record

ArticlebioRxiv : the preprint server for biology2026

MORPHE: Bridging Image Generation and Spatial Omics for Tissue Synthesis.

Yuan Feng, Zachary Robers, Leyla Rasheed, Yang Miao, Shuo Wen, Kevin Lee, James Sohigian, Maria Brbić, John W Hickey

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Yuan FengDepartment of Biomedical Engineering, Duke University, Durham, NC, 27708, USA.
Zachary RobersDepartment of Computer Science, Duke University, Durham, NC, 27708, USA.
Leyla RasheedDepartment of Computer Science, Duke University, Durham, NC, 27708, USA.
Yang MiaoDepartment of Biomedical Engineering, Duke University, Durham, NC, 27708, USA.
Shuo WenSchool of Computer and Communication Sciences, EPFL, Lausanne CH-1015, Switzerland.
Kevin LeeDepartment of Computer Science, Duke University, Durham, NC, 27708, USA.
James SohigianDepartment of Computer Science, Duke University, Durham, NC, 27708, USA.
Maria BrbićSchool of Computer and Communication Sciences, EPFL, Lausanne CH-1015, Switzerland.
John W HickeyDepartment of Biomedical Engineering, Duke University, Durham, NC, 27708, USA.ORCID 0000-0001-9961-7673

Funding

Flexible Hybrid Cloud Infrastructure for Seamless Integration and Use of Human Biomolecular Data and Reference Maps [1 of 5]OT2OD033759 · OD · CARNEGIE-MELLON UNIVERSITY · PI BLOOD, PHILIP D., SILVERSTEIN, JONATHAN C. · 2022 to 2025
$20.4M
Model and Data Sharing CoreU54AI191253 · NIAID · DUKE UNIVERSITY · PI Cliburn C Chan · 2025 to 2026
$16.4M
Multiscale Modeling of Influenza Neutralizing Antibody and Fc Effector BiologyU01AI186999 · NIAID · DUKE UNIVERSITY · PI Cliburn C Chan, Roger Keith Reeves · 2025 to 2026
$2.1M
NIAID NIH HHS U01 AI186999NIAID NIH HHS U54 AI191253NIH HHS OT2 OD033759
6 · The paper itself

Abstract

Spatially resolved omics technologies reveal tissue organization at single-cell resolution but remain limited by the cost of the assays, incomplete spatial coverage, 2D-only imaging, and experimental artifacts. These factors motivate the need for

Identifiers

PMID41867722
PMCPMC13001316

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.