ArticlebioRxiv : the preprint server for biology2026
Disrupted O-GalNAc glycosylation as a mechanism and biomarker of
Abstract readPreprint
In one paragraph
Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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0citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
26 authors.
Robert G MealerDepartment of Psychiatry, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.ORCID 0000-0001-5963-2836
James J AndersonInstitute for Genomic Medicine, Nationwide Children's Hospital, Columbus, OH 43215, USA.ORCID 0009-0004-7326-5787
Sheridan L SmithDepartment of Psychiatry, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.ORCID 0009-0002-0793-0705
Brianna M MastersDepartment of Psychiatry, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.ORCID 0009-0006-6258-3565
Samuel H BarthNeuroscience Center, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.ORCID 0000-0003-4823-3076
Kaitlyn D J HuizarDepartment of Genetics, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.ORCID 0009-0005-6055-7091
Sahibjot SranInstitute for Genomic Medicine, Nationwide Children's Hospital, Columbus, OH 43215, USA.ORCID 0000-0001-7621-0619
Hyojung YoonInstitute for Genomic Medicine, Nationwide Children's Hospital, Columbus, OH 43215, USA.ORCID 0000-0002-1376-9527
Amanda RinglandInstitute for Genomic Medicine, Nationwide Children's Hospital, Columbus, OH 43215, USA.
Savannah J MuronDepartment of Genetics, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.ORCID 0000-0002-3252-2001
MaryAnn E BowyerDivision of Pharmacotherapy and Experimental Therapeutics, Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, NC, 27599, USA.ORCID 0009-0001-7452-7759
Alissa M D'GamaF.M. Kirby Neurobiology Center, Boston Children's Hospital, Boston, MA 02115, USA.ORCID 0000-0002-2482-5328
Annapurna PoduriF.M. Kirby Neurobiology Center, Boston Children's Hospital, Boston, MA 02115, USA.
Hart G W LidovDepartment of Pathology, Boston Children's Hospital, Harvard Medical School, Boston, MA 02115, USA.
Edward YangDepartment of Radiology, Boston Children's Hospital, Harvard Medical School, Boston, MA 02115, USA.
Julia FurnariDepartment of Neurological Surgery, Columbia University Irving Medical Center, New York, NY 10032, USA.
Peter D CanollDepartment of Pathology and Cell Biology, Columbia University, New York, NY, USA.
Adam P OstendorfDepartment of Pediatrics, Ohio State University, Columbus, OH 43215, USA.ORCID 0000-0002-9994-6650
Daniel C KoboldtInstitute for Genomic Medicine, Nationwide Children's Hospital, Columbus, OH 43215, USA.
Christopher R PiersonDepartment of Pathology and Laboratory Medicine, Nationwide Children's Hospital, Columbus, OH, USA.ORCID 0000-0002-5553-3096
Diana L ThomasDepartment of Pathology and Laboratory Medicine, Nationwide Children's Hospital, Columbus, OH, USA.
Benjamin D PhilpotNeuroscience Center, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.ORCID 0000-0003-2746-9143
Maxence NoelDepartment of Surgery, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA.ORCID 0000-0003-2621-7374
Richard D CummingsDepartment of Surgery, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA.ORCID 0000-0002-8918-5034
Erin L HeinzenDepartment of Genetics, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.ORCID 0000-0002-7268-8559
Tracy A BedrosianInstitute for Genomic Medicine, Nationwide Children's Hospital, Columbus, OH 43215, USA.ORCID 0000-0002-1051-9100
Funding
Virology Research Program (Program 4)P30CA016086 · NCI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Deborah F. Tate · 1985 to 2026
$201.5MUNC Neuroscience Center Research Cores: MicroscopyP30NS045892 · NINDS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI ZYLKA, MARK J. · 2003 to 2022
$11.5MRESEARCH TRAINING IN THE NEUROSCIENCEST32NS007431 · NINDS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Juan Song, Mark J. Zylka · 1997 to 2026
$10.0MPreclinical CoreP50HD103573 · NICHD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI GABRIEL S DICHTER · 2020 to 2026
$9.7MPostdoctoral Research in Neurodevelopmental DisordersT32HD040127 · NICHD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI BENJAMIN D PHILPOT, Mark D Shen · 2001 to 2026
$8.5MIdentification and molecular characterization of somatic mutations in MCDR01NS094596 · NINDS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Peter B Crino, Erin L HEINZEN · 2016 to 2026
$5.9MNRSA in GeneticsT32GM135128 · NIGMS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Daniel J McKay, JEFF J. SEKELSKY · 2020 to 2026
$5.1MDefining disease mechanisms in SLC35A2 epilepsyR01NS115017 · NINDS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI CRINO, PETER B, HEINZEN, ERIN L · 2020 to 2024
$3.7MSomatic Mutation in Intractable Focal EpilepsyR01NS114122 · NINDS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI CRINO, PETER B, HEINZEN, ERIN L · 2020 to 2024
$3.3MDeciphering brain mosaicism in drug-resistant epilepsy at cellular resolutionR01NS129784 · NINDS · RESEARCH INST NATIONWIDE CHILDREN'S HOSP · PI Tracy Ann Bedrosian · 2023 to 2026
$2.2MInvestigating UBE3A as a driver gene in Duplication 15q syndromeR01NS129914 · NINDS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI BENJAMIN D PHILPOT · 2023 to 2026
$1.6MSynaptic dysglycosylation caused by the schizophrenia-risk variant in SLC39A8K08MH128712 · NIMH · UNIV OF NORTH CAROLINA CHAPEL HILL · PI MEALER, ROBERT G · 2021 to 2024
$771kNCI NIH HHS P30 CA016086NICHD NIH HHS P50 HD103573NICHD NIH HHS T32 HD040127NIGMS NIH HHS T32 GM135128NIMH NIH HHS K08 MH128712NINDS NIH HHS K23 NS140397NINDS NIH HHS P30 NS045892NINDS NIH HHS R01 NS094596NINDS NIH HHS R01 NS114122NINDS NIH HHS R01 NS115017NINDS NIH HHS R01 NS129784NINDS NIH HHS R01 NS129914NINDS NIH HHS T32 NS007431
Abstract
Rare germline and somatic variants in
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Read underepoch 390
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.