Evidence map›Paper›PMID 41867715›Full record

ArticlebioRxiv : the preprint server for biology2026

Metabolic stress reveals widespread accumulation of cap-unmethylated RNAs.

Zheng Xing, Anna Violet Freitas, Benjamin M Sutter, Ngoc Khoi Dang, Nicholas T Ingolia, Benjamin P Tu

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Zheng XingDepartment of Biochemistry, University of Texas Southwestern Medical Center, Dallas, TX, USA.
Anna Violet FreitasDepartment of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA, USA.
Benjamin M SutterDepartment of Biochemistry, University of Texas Southwestern Medical Center, Dallas, TX, USA.
Ngoc Khoi DangLyda Hill Department of Bioinformatics, University of Texas Southwestern Medical Center, Dallas, TX, USA.
Nicholas T IngoliaDepartment of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA, USA.ORCID 0000-0002-3395-1545
Benjamin P TuDepartment of Biochemistry, University of Texas Southwestern Medical Center, Dallas, TX, USA.ORCID 0000-0001-5545-9183

Funding

Metabolic signals regulating cell growth versus survivalR35GM136370 · NIGMS · UT SOUTHWESTERN MEDICAL CENTER · PI Benjamin P Tu · 2020 to 2026
$2.8M
Diverse and dynamically regulated mRNP composition regulating translationR01GM139008 · NIGMS · UNIVERSITY OF CALIFORNIA BERKELEY · PI NICHOLAS T INGOLIA · 2023 to 2026
$1.2M
NIGMS NIH HHS R01 GM139008NIGMS NIH HHS R35 GM136370
6 · The paper itself

Abstract

RNA polymerase II transcripts are capped with N

Identifiers

PMID41867715
PMCPMC13004159

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.