Evidence map›Paper›PMID 41867708›Full record

ArticlebioRxiv : the preprint server for biology2026

Parasite defense covaries with reproductive timing, not with resistance.

Amanda K Gibson, Linyao Peng, Tessa Batterton, Neha Channamraju, Victoria Feist, Sarah Hesse, Anne N Janisch, Hongyi Shui

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors.

Amanda K GibsonDepartment of Biology, University of Virginia, Charlottesville, VA, USA.ORCID 0000-0002-0867-4953
Linyao PengDepartment of Biology, University of Virginia, Charlottesville, VA, USA.
Tessa BattertonDepartment of Biology, University of Virginia, Charlottesville, VA, USA.
Neha ChannamrajuDepartment of Biology, University of Virginia, Charlottesville, VA, USA.
Victoria FeistDepartment of Biology, University of Virginia, Charlottesville, VA, USA.ORCID 0009-0008-5075-9708
Sarah HesseDepartment of Biology, University of Virginia, Charlottesville, VA, USA.
Anne N JanischDepartment of Biology, University of Virginia, Charlottesville, VA, USA.
Hongyi ShuiIndependent researcher, Charlottesville, VA, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Parasite defense is the ability of a host to minimize fitness loss to parasites, and it is among the most variable phenotypes in natural populations. We expect this variation in defense to facilitate rapid adaptation under parasite-mediated selection. What we do not know is what traits are most likely to evolve in response to this selection. A common assumption is that the most defended hosts are the most resistant, meaning they limit the establishment and growth of infecting parasites. Under this assumption, resistance traits should evolve readily under parasite selection. Resistance is, however, just one of many strategies hosts use to defend against parasites, and it does not consistently covary with parasite defense. We accordingly ask: which host traits covary with parasite defense and are thus likely to respond to parasite selection? We use controlled exposures to characterize genetic variation in defense of the nematode

Identifiers

PMID41867708
PMCPMC13001419

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.