Evidence map›Paper›PMID 41867599›Full record

ArticleACS omega2026

Expression, Solubilization, and Refolding Recovery of a Novel l‑Asparaginase-Arginase 1 Chimera from

Massiel V Rivera, Marina Gabriel Fontes, William Henry Roldán, Roberto Carlos Vieira da Silva Junior, Lisandra Herrera Belén, Jorge F Beltrán, Igor Lopes-Silva, Adalberto Pessoa, Marco A Stephano, Jorge G Farias and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ACS omega, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Massiel V RiveraDepartamento de Tecnologia Bioquímica-Farmacêutica, Faculdade de Ciências Farmacêuticas, Universidade de São Paulo, São Paulo 05508-000, Brazil.ORCID https://orcid.org/0000-0002-6779-519X
Marina Gabriel FontesDepartamento de Tecnologia Bioquímica-Farmacêutica, Faculdade de Ciências Farmacêuticas, Universidade de São Paulo, São Paulo 05508-000, Brazil.
William Henry RoldánDepartamento de Tecnologia Bioquímica-Farmacêutica, Faculdade de Ciências Farmacêuticas, Universidade de São Paulo, São Paulo 05508-000, Brazil.
Roberto Carlos Vieira da Silva JuniorDepartamento de Tecnologia Bioquímica-Farmacêutica, Faculdade de Ciências Farmacêuticas, Universidade de São Paulo, São Paulo 05508-000, Brazil.
Lisandra Herrera BelénDepartamento de Ciencias Básicas, Facultad de Ciencias, Universidad Santo Tomás, Temuco 4780000, Chile.
Jorge F BeltránDepartamento de Ingeniería Química, Facultad de Ingeniería y Ciencias, Universidad de La Frontera, Temuco 4811230, Chile.
Igor Lopes-SilvaDepartamento de Tecnologia Bioquímica-Farmacêutica, Faculdade de Ciências Farmacêuticas, Universidade de São Paulo, São Paulo 05508-000, Brazil.
Adalberto PessoaDepartamento de Tecnologia Bioquímica-Farmacêutica, Faculdade de Ciências Farmacêuticas, Universidade de São Paulo, São Paulo 05508-000, Brazil.
Marco A StephanoDepartamento de Tecnologia Bioquímica-Farmacêutica, Faculdade de Ciências Farmacêuticas, Universidade de São Paulo, São Paulo 05508-000, Brazil.
Jorge G FariasDepartamento de Ingeniería Química, Facultad de Ingeniería y Ciencias, Universidad de La Frontera, Temuco 4811230, Chile.
Tales Alexandre Costa-SilvaCenter for Natural and Human Sciences, Federal University of ABC, Santo André, São Paulo 09280-560, Brazil.
Gisele MonteiroDepartamento de Tecnologia Bioquímica-Farmacêutica, Faculdade de Ciências Farmacêuticas, Universidade de São Paulo, São Paulo 05508-000, Brazil.ORCID https://orcid.org/0000-0002-3385-047X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The preparative expression, purification, and refolding of a novel bifunctional chimeric enzyme, 63

Identifiers

PMID41867599
PMCPMC13000580

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.