Evidence map›Paper›PMID 41867474›Full record

ReviewJournal of biomedical optics2026

Perspective on the current state of hyperspectral/multispectral imaging for minimally invasive surgery.

Mark Witteveen, Cyrille Mooij, Behdad Dashtbozorg, Theo Ruers

Abstract readReview
In one paragraph

Review in Journal of biomedical optics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Mark WitteveenNetherlands Cancer Institute, Image-Guided Surgery, Surgical Oncology, Amsterdam, The Netherlands.ORCID https://orcid.org/0000-0002-8290-3582
Cyrille MooijNetherlands Cancer Institute, Image-Guided Surgery, Surgical Oncology, Amsterdam, The Netherlands.ORCID https://orcid.org/0009-0006-7032-1864
Behdad DashtbozorgNetherlands Cancer Institute, Image-Guided Surgery, Surgical Oncology, Amsterdam, The Netherlands.
Theo RuersNetherlands Cancer Institute, Image-Guided Surgery, Surgical Oncology, Amsterdam, The Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Significance: Minimally invasive surgery (MIS) offers substantial benefits to patients, including reduced trauma and faster recovery. However, it limits visual and tactile feedback, which can affect surgical decision-making. Hyperspectral and multispectral imaging (HSI/MSI) are imaging technologies with the potential to provide detailed, real-time tissue characterization, enhancing minimally invasive intraoperative guidance. Aim: This perspective aims to summarize the current state-of-the-art in the use of HSI/MSI in laparoscopy and endoscopy. It focuses on both technological development and clinical implementation, providing an overview of performance characteristics and translational state. Approach: A structured literature search was conducted to identify relevant studies. These were analyzed for key system specifications (spectral range, resolution, and acquisition speed) and clinical applications. The studies were further categorized using a "bench-to-bedside" framework to evaluate their level of translational progress. Results: The majority of studies fall within early translational stages (T1 to T2), with no reports of large-scale clinical trials. Most systems operate in the visible spectrum (450 to 650 nm), optimized for blood-related imaging. Applications include perfusion assessment, nerve visualization using short-wave infrared wavelengths, and tumor detection. Conclusions: HSI/MSI for MIS is a rapidly developing field with demonstrated potential across a range of applications. Continued research and validation are essential to transition these technologies from experimental use to routine surgical practice.

Indexed as

Hyperspectral ImagingMinimally Invasive Surgical ProceduresAnimalsEndoscopyHumansLaparoscopybench-to-bedsidehyperspectral imaginglaparoscopyliterature searchminimally invasive surgerymultispectral imaging

Identifiers

PMID41867474
PMCPMC13002860

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.