SNTB1 gene polymorphisms and risk of high myopia: meta-analysis and single-center validation.

Jie Peng, Yina Wang, Jiaqing Lu, Ying Wang, Yongning Dong, Jie Fang, Xu Chen

Abstract readMeta-Analysis

In one paragraph

Synthesis in Molecular vision, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jie PengWuxi Huishan District People's Hospital, Wuxi, China.

Yina WangAffiliated Hospital of Jiangnan University, Wuxi, China.

Jiaqing LuAffiliated Hospital of Jiangnan University, Wuxi, China.

Ying WangWuxi School of Medicine, Jiangnan University, Wuxi, China.

Yongning DongWuxi School of Medicine, Jiangnan University, Wuxi, China.

Jie FangWuxi Huishan District People's Hospital, Wuxi, China.

Xu ChenWuxi Huishan District People's Hospital, Wuxi, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: Genetic polymorphisms in syntrophin beta-1 (SNTB1) have been implicated in altering protein function or expression, potentially influencing ocular growth regulation. Genome-wide association studies (GWASs) suggest that specific Methods: Accordingly, the PubMed and Wanfang databases were searched for articles published until June 1, 2025, using the keywords Results: Four related studies were conducted to better understand the association between Conclusions: The current study suggested that the

Indexed as

Dystrophin-Associated ProteinsGenetic Predisposition to DiseaseMyopiaPolymorphism, Single NucleotideCase-Control StudiesGenome-Wide Association StudyGenotypeHumansOdds RatioRisk FactorsDystrophin-Associated Proteinssyntrophin

Identifiers

PMID41867379

PMCPMC13002932

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.