Evidence map›Paper›PMID 41867309›Full record

ArticleACS environmental Au2026

Sublethal Effects of the Insect Growth Regulator Novaluron on the Midgut Integrity and Survival of Adult Honey Bee

Mateus Soares de Oliveira, João Victor de Oliveira Motta, Davy Soares Gomes, Giovanna Dos Santos Pereira, Gabriel Martins Pantoja, Laryssa Lemos da Silva, João Paulo Pimentel de Oliveira Cruz, José Eduardo Serrão

Abstract read
In one paragraph

Article in ACS environmental Au, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Mateus Soares de OliveiraDepartment of General Biology, Federal University of Viçosa, Viçosa, Minas Gerais 36570-900, Brazil.
João Victor de Oliveira MottaDepartment of General Biology, Federal University of Viçosa, Viçosa, Minas Gerais 36570-900, Brazil.
Davy Soares GomesDepartment of General Biology, Federal University of Viçosa, Viçosa, Minas Gerais 36570-900, Brazil.
Giovanna Dos Santos PereiraDepartment of Entomology, Federal University of Viçosa, Viçosa, Minas Gerais 36570-900, Brazil.
Gabriel Martins PantojaDepartment of General Biology, Federal University of Viçosa, Viçosa, Minas Gerais 36570-900, Brazil.
Laryssa Lemos da SilvaDepartment of General Biology, Federal University of Viçosa, Viçosa, Minas Gerais 36570-900, Brazil.
João Paulo Pimentel de Oliveira CruzDepartment of General Biology, Federal University of Viçosa, Viçosa, Minas Gerais 36570-900, Brazil.
José Eduardo SerrãoDepartment of General Biology, Federal University of Viçosa, Viçosa, Minas Gerais 36570-900, Brazil.ORCID https://orcid.org/0000-0002-0477-4252

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The insect growth regulator novaluron is a benzoylurea compound that disrupts the polymerization of chitin filaments. It is commonly used to control agricultural pests, particularly during their immature stages, and is generally considered nontoxic to adult insects. However, there is a lack of studies addressing the potential side effects of this insecticide on nontarget organisms, such as pollinating bees. In honey bees, the midgut is the primary organ responsible for digestion and nutrient absorption, where ingested food is surrounded by the peritrophic matrix, a structure composed of chitin microfibrils, glycosaminoglycans, and glycoproteins synthesized by digestive cells along the midgut. This study investigated whether chronic oral exposure to novaluron affects adult workers of the honey bee

Indexed as

benzoylureachitinhistopathologypesticiderisk assessment

Identifiers

PMID41867309
PMCPMC13003356

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.