SigmaScheduling: Uncertainty-Informed Scheduling of Decision Points for Intelligent Mobile Health Interventions.

Timely decision making is critical to the effectiveness of mobile health (mHealth) interventions. At predefined timepoints called "decision points," intelligent mHealth systems such as just-in-time adaptive interventions (JITAIs) estimate an individual's biobehavioral context from sensor or survey data and determine whether and how to intervene. For interventions targeting habitual behavior (e.g., oral hygiene), effectiveness often hinges on delivering support shortly before the target behavior is likely to occur. Current practice schedules decision points at a fixed interval (e.g., one hour) before user-provided behavior times, and the fixed interval is kept the same for all individuals. However, this one-size-fits-all approach performs poorly for individuals with irregular routines, often scheduling decision points after the target behavior has already occurred, rendering interventions ineffective. In this paper, we propose SigmaScheduling, a method to dynamically schedule decision points based on uncertainty in predicted behavior times. When behavior timing is more predictable, SigmaScheduling schedules decision points closer to the predicted behavior time; when timing is less certain, SigmaScheduling schedules decision points earlier, increasing the likelihood of timely intervention. We evaluated SigmaScheduling using real-world data from 68 participants in a 10-week trial of Oralytics, a JITAI designed to improve daily toothbrushing. SigmaScheduling increased the likelihood that decision points preceded brushing events in at least 70% of cases, preserving opportunities to intervene and impact behavior. Our results indicate that SigmaScheduling can advance precision mHealth, particularly for JITAIs targeting time-sensitive, habitual behaviors such as oral hygiene or dietary habits.