Evidence map›Paper›PMID 41867213›Full record

ArticlemedRxiv : the preprint server for health sciences2026

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Caroline Watiri, Juddy Wachira, Benson Njuguna, Jessica Gjonaj, Kibet Kangogo, Mercy Korir, Jeremiah Laktabai, Imran Manji, Sonak D Pastakia, Dan N Tran and 1 more

Registry-linked trialAbstract readPreprint
In one paragraph

Article in medRxiv : the preprint server for health sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05051124 (PT4A), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05051124 nacompletednot on this map

PT4A (Peers and Technology for Adherence, Access, Accountability, and Analytics) - A Qualitative Study

TypeinterventionalSponsorNYU Langone HealthRan2022 to 2024Enrolled101ConditionsHypertension, Medication AdherenceArmsPeer Delivery of Medications, Health Information Technology (HIT) Platform
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Caroline WatiriAcademic Model Providing Access to Healthcare, Eldoret, Kenya.
Juddy WachiraAcademic Model Providing Access to Healthcare, Eldoret, Kenya.
Benson NjugunaMoi Teaching and Referral Hospital, Kenya.
Jessica GjonajInstitute for Excellence in Health Equity, NYU Grossman School of Medicine, New York, USA.ORCID 0009-0001-9454-9349
Kibet KangogoAcademic Model Providing Access to Healthcare, Eldoret, Kenya.
Mercy KorirAcademic Model Providing Access to Healthcare, Eldoret, Kenya.
Jeremiah LaktabaiMoi University, Eldoret, Kenya.
Imran ManjiMoi Teaching and Referral Hospital, Kenya.
Sonak D PastakiaPurdue University, Indianapolis, USA.
Dan N TranTemple University School of Pharmacy, Department of Pharmacy Practice, Philadelphia, USA.
Rajesh VedanthanInstitute for Excellence in Health Equity, NYU Grossman School of Medicine, New York, USA.ORCID 0000-0001-7138-2382

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: In low- and middle-income countries, the burden of hypertension is increasing. Medication adherence is a critical component of reducing hypertension-related cardiovascular disease (CVD) risk and death. There are many barriers to hypertension medication adherence, including challenges with access to and possession of medication. To address these challenges, we aim to implement a strategy in rural western Kenya that combines peer delivery of medications and health information technology to improve hypertension medication possession and adherence. Recognizing that stakeholder experience and knowledge can be useful to optimize successful implementation, we sought to assess micro- and macro-level stakeholder perceptions of the planned implementation strategy. Methods: Focus group discussions in both English and Kiswahili were conducted among people living with hypertension, community members, and health workers. In addition, key informant interviews were conducted with public sector health administrators including the program/policy planners for non-communicable diseases at the national and county levels. Content analysis of all transcripts was conducted. A codebook containing deductive codes was generated based on Results: The PT4A implementation strategy was perceived to have both benefits and potential challenges. Major themes included the importance of trust resulting from a safe space to share experiences with peers, increased access to medications, improved hypertension management at the facility and community levels, and anticipated improved health outcomes for people living with hypertension. The success of the program was felt to rely heavily on the peers' competency and how well they communicated, which was viewed as a potential challenge by some stakeholders. Areas of consensus expressed across all participant groups were mostly focused on patient psychosocial support and access to medications. Conclusion: This study was able to identify key perceptions elicited for an implementation strategy that combines peer medication delivery and health information technology to improve hypertension medication adherence. Pre-implementation stakeholder engagement can unearth unique perspectives around perceived benefits and challenges that can be used to refine strategies to increase the success of implementing evidence-based interventions in new contexts. ClinicalTrialsgov identifier NCT number: NCT05051124.

Identifiers

PMID41867213
PMCPMC13004099

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.