ArticlePalliative & supportive care2026
Beyond medication: Understanding child and caregiver perspectives on multifaceted adherence in pediatric hematopoietic stem cell transplantation.
Article in Palliative & supportive care, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
objectivesThis qualitative study sought to explore the unique experiences of children receiving hematopoietic stem cell transplant (HCT) and their caregivers, with a primary focus on the multifaceted aspects of adherence following discharge.
methodsConvenience sampling was used to enroll 14 caregivers and 15 children at a large Midwestern children's hospital. Children had an allogenic HCT for a malignant or nonmalignant disorder and were 1-12 months off immunosuppression. Participants completed a semi-structured interview in the HCT-clinic or via phone about the child's experience taking medications and adhering to post-transplant guidelines.
resultsCaregivers were primarily female ( SIGNIFICANCE OF
resultsThis study contributes a nuanced understanding of adherence in pediatric HCT, emphasizing the need for tailored interventions that transcend traditional medical frameworks and enable clear communication between families and the medical team. Findings underscore the importance of providers adopting a comprehensive and patient-centered approach. Healthcare providers should consider the psychosocial aspects of HCT, implement tailored family-centered strategies to optimize adherence, and prioritize comprehensive communication to improve outcomes.
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