Article in Hypertension (Dallas, Tex. : 1979), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registry
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Longgang ZhaoYale School of Nursing, Orange, CT (Y.C., L.Z., Xuehong Zhang).ORCID 0000-0001-9254-1952
Yinan ZhengDepartment of Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL (Y.Z., T.G., Y.Q., H.N., J.T.W., M.R.C., N.B.A., L.H.).ORCID 0000-0002-2006-7320
John Jeffrey CarrDepartment of Radiology and Radiological Sciences, Vanderbilt University School of Medicine, Nashville, TN (J.J.C., J.G.T.).ORCID 0000-0002-4398-8237
Tao GaoDepartment of Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL (Y.Z., T.G., Y.Q., H.N., J.T.W., M.R.C., N.B.A., L.H.).
James G TerryDepartment of Radiology and Radiological Sciences, Vanderbilt University School of Medicine, Nashville, TN (J.J.C., J.G.T.).ORCID 0000-0001-6659-3441
Yishu QuDepartment of Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL (Y.Z., T.G., Y.Q., H.N., J.T.W., M.R.C., N.B.A., L.H.).ORCID 0000-0001-5937-3811
Hongyan NingDepartment of Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL (Y.Z., T.G., Y.Q., H.N., J.T.W., M.R.C., N.B.A., L.H.).ORCID 0000-0003-1157-6614
Xinyuan ZhangChanning Division of Network Medicine and Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA (Xinyuan Zhang).ORCID 0000-0002-2974-8392
John T WilkinsDepartment of Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL (Y.Z., T.G., Y.Q., H.N., J.T.W., M.R.C., N.B.A., L.H.).ORCID 0000-0002-8781-1329
Sejong BaeDepartment of Biostatistics, Data Science, and Epidemiology, Augusta University, Augusta, GA (S.B.).ORCID 0000-0001-9982-3223
Mercedes R CarnethonDepartment of Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL (Y.Z., T.G., Y.Q., H.N., J.T.W., M.R.C., N.B.A., L.H.).ORCID 0000-0001-7035-0848
Norrina B AllenDepartment of Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL (Y.Z., T.G., Y.Q., H.N., J.T.W., M.R.C., N.B.A., L.H.).ORCID 0000-0002-6993-4384
David R JacobsDivision of Epidemiology and Community Health, School of Public Health, University of Minnesota, Minneapolis, MN (D.R.J.).ORCID 0000-0002-7232-0543
Donald M Lloyd-JonesChobanian and Avedisian School of Medicine, Boston University, Boston, MA (D.M.L.-J.).ORCID 0000-0003-0847-6110
Lifang Hou *Department of Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL (Y.Z., T.G., Y.Q., H.N., J.T.W., M.R.C., N.B.A., L.H.).ORCID 0000-0003-4877-0031
Xuehong Zhang *Yale School of Nursing, Orange, CT (Y.C., L.Z., Xuehong Zhang).ORCID 0000-0002-8260-8508
Funding
CORONARY ARTERY RISK DEVELOPMENT IN YOUNG ADULTS (CARDIA) STUDY - COORDINATING CENTER (CC)75N92023D00002 · NHLBI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI LI, JING · 2023 to 2025
$6.8M
Decoding mechanisms underlying metabolic dysregulation in obesity and digestive cancer riskU01CA272452 · NCI · BRIGHAM AND WOMEN'S HOSPITAL · PI GIOVANNUCCI, EDWARD, TOBIAS, DEIRDRE KAY · 2022 to 2025
$6.4M
CORONARY ARTERY RISK DEVELOPMENT IN YOUNG ADULTS (CARDIA) STUDY - OAKLAND FIELD CENTER75N92023D00003 · NHLBI · KAISER FOUNDATION RESEARCH INSTITUTE · PI BHATT, ANKEET S. · 2023 to 2025
$2.2M
CORONARY ARTERY RISK DEVELOPMENT IN YOUNG ADULTS (CARDIA) STUDY - BIRMINGHAM FIELD CENTER75N92023D00005 · NHLBI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI LEWIS, CORA · 2023 to 2025
$2.2M
CORONARY ARTERY RISK DEVELOPMENT IN YOUNG ADULTS (CARDIA) STUDY - CHICAGO FIELD CENTERDIVERSITY SUPPLEMENT FOR MORGANN WEST75N92023D00004 · NHLBI · NORTHWESTERN UNIVERSITY · PI CARNETHON, MERCEDES · 2023 to 2025
$2.1M
CORONARY ARTERY RISK DEVELOPMENT IN YOUNG ADULTS (CARDIA) STUDY - UNIVERSITY OF MINNESOTA FIELD CENTER.75N92023D00006 · NHLBI · UNIVERSITY OF MINNESOTA · PI SCHREINER, PAMELA J · 2023 to 2025
backgroundAlthough high blood pressure (BP) is a risk factor for steatotic liver disease (SLD), whether longitudinal BP trajectories starting in young adulthood are associated with midlife SLD is unclear.
methodsWe used data from a US-based prospective cohort, the CARDIA study (Coronary Artery Risk Development in Young Adults), which enrolled 5115 Black and White adults aged 18 to 30 years in 1985 to 1986 (Year 0, Y0). Diastolic and systolic BP and hypertension trajectories were evaluated based on up to 8 BP measures over a 25-year follow-up. SLD at Y25 was measured using noncontrast abdominal computed tomography scans.
resultsAmong 2817 participants included in the analytic sample, 622 SLD cases were identified. Compared with the low-stable diastolic BP group, other trajectories showed higher SLD prevalence (22.0%-37.5% versus 12.8%), with multivariable-adjusted relative risks of 1.47 (95% CI, 1.17-1.84) for moderate-stable, 1.77 (1.33-2.35) for moderate-increasing (remaining below the threshold for hypertension), 1.57 (1.21-2.04) for elevated-stable, and 2.02 (1.41-2.88) for the elevated-increasing trajectory. Similar positive associations were observed for systolic BP trajectories. Compared with those persistently normotensive, participants who developed hypertension had significantly higher SLD risks: 1.62-fold for late-onset and 1.75-fold for both mid-adulthood and early onset. Consistently, a faster rate of BP increase was linked to higher SLD risk.
conclusionsLong-term BP and hypertension patterns in young adulthood were independently associated with increased midlife SLD risk, with rapidly increasing BP exhibiting the greatest risk. Long-term BP changes may assist in more accurate identification of individuals at higher risk of SLD.
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.
Blood Pressure Trajectories in Young Adulthood and Midlife Steatotic Liver Disease. · full record | OpenQuestion