ArticleKorean circulation journal2026
Clinical Implications and Evolution of Significant Tricuspid Regurgitation in Patients Undergoing Left Ventricular Assist Device Implantation.
Article in Korean circulation journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Tricuspid Regurgitation Can Improve After LVAD: Right Ventricular Reserve Should Not Be Overlooked.Korean circulation journal · 2026Article
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND AND
objectivesTricuspid regurgitation (TR) is common in advanced heart failure patients undergoing left ventricular assist device (LVAD) implantation, yet its independent prognostic value and post-LVAD trajectory remain uncertain.
methodsThis retrospective single-center study included 178 patients who underwent LVAD implantation without concomitant tricuspid valve intervention (TVI) between 2012 and 2024. Patients were stratified based on preoperative echocardiography into non-significant TR (n=141) and significant (≥ moderate) TR (n=37). Primary outcomes were early right ventricular (RV) failure, all-cause mortality and heart failure hospitalization.
resultsSignificant baseline TR independently predicted early RV failure (odds ratio, 2.38; 95% confidence interval, 1.04 to 5.70; p=0.041), but was not associated with long-term outcomes, including all-cause mortality or heart failure hospitalization. During follow-up, TR severity improved in 60% of patients and most patients achieved hemodynamic optimization regardless of baseline TR severity. Functional recovery was observed in both groups, with a greater tendency of 6-minute walk improvement in patients with significant TR (p=0.057).
conclusionsBaseline moderate-to-severe TR predicts early RV failure but not long-term adverse outcomes following LVAD implantation. Most patients experience spontaneous TR improvement and achieve similar hemodynamic optimization regardless of baseline TR severity. These findings suggest LVAD support alone promotes RV reverse remodeling without requiring routine concomitant TVI.
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