Evidence map›Paper›PMID 41866801›Full record

ArticleStem cells translational medicine2026

Autologous stem cell transplant for severe, progressive juvenile systemic sclerosis.

Shaikha Alqahtani, Fabiana Cacace, Andrea Bauchat, Brittany Paige DePriest, Timothy Alan Driscoll, Carmem Bonfim, Joanne Kurtzberg, Nicole Larrier, Jeffery Dvergsten, Kris Michael Mahadeo

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Stem cells translational medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Shaikha AlqahtaniPediatric Transplant and Cellular Therapy, Duke University, Durham, NC 27705, United States.ORCID 0009-0004-1176-8952
Fabiana CacacePediatric Transplant and Cellular Therapy, Duke University, Durham, NC 27705, United States.
Andrea BauchatPediatric Transplant and Cellular Therapy, Duke University, Durham, NC 27705, United States.ORCID 0009-0006-4220-3123
Brittany Paige DePriestPediatric Transplant and Cellular Therapy, Duke University, Durham, NC 27705, United States.
Timothy Alan DriscollPediatric Transplant and Cellular Therapy, Duke University, Durham, NC 27705, United States.
Carmem BonfimPediatric Transplant and Cellular Therapy, Duke University, Durham, NC 27705, United States.
Joanne KurtzbergPediatric Transplant and Cellular Therapy, Duke University, Durham, NC 27705, United States.ORCID 0000-0002-3370-0703
Nicole LarrierDepartment of Radiation Oncology, Duke University, Durham, NC 27703, United States.
Jeffery DvergstenDepartment of Pediatric Rheumatology, Duke University, Durham, NC 27703, United States.
Kris Michael MahadeoPediatric Transplant and Cellular Therapy, Duke University, Durham, NC 27705, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Juvenile systemic sclerosis (jSSc) is a rare, chronic, autoimmune disease in children/adolescents and is associated with significant morbidity, skin thickening/hardening (scleroderma), organ toxicity and sub-optimal therapeutic options. In this report, autologous stem cell transplantation is associated with clinical improvement in a 17-year-old with refractory jSSc.

Indexed as

Scleroderma, SystemicStem Cell TransplantationAdolescentHumansMaleTransplantation, Autologousautologous stem cell transplantjuvenile systemic sclerosispediatric rheumatologypediatric stem cell transplantrefractory autoimmune disease

Identifiers

PMID41866801
PMCPMC13006201

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.