Evidence map›Paper›PMID 41866609›Full record

ArticleIntensive care medicine experimental2026

Setting PEEP in patients with COVID-19-related ARDS: a physiological comparison between methods.

Dolf Weller, Peter Somhorst, Corstiaan den Uil, Diederik Gommers, Annemijn H Jonkman

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Article in Intensive care medicine experimental, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Dolf Weller *Department of Adult Intensive Care, Erasmus Medical Centre, Dr. Molewaterplein 40, 3015 GD, Rotterdam, The Netherlands. d.weller@erasmusmc.nl.ORCID http://orcid.org/0000-0003-3153-5764
Peter Somhorst *Department of Adult Intensive Care, Erasmus Medical Centre, Dr. Molewaterplein 40, 3015 GD, Rotterdam, The Netherlands. p.somhorst@erasmusmc.nl.
Corstiaan den UilDepartment of Intensive Care, Maasstad Hospital, Rotterdam, The Netherlands.
Diederik GommersDepartment of Adult Intensive Care, Erasmus Medical Centre, Dr. Molewaterplein 40, 3015 GD, Rotterdam, The Netherlands.
Annemijn H JonkmanDepartment of Adult Intensive Care, Erasmus Medical Centre, Dr. Molewaterplein 40, 3015 GD, Rotterdam, The Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSeveral approaches for setting PEEP in patients with (COVID-19-related) ARDS have been proposed. It is unclear whether a best approach exist, and how the recommended PEEP and resulting transpulmonary pressure, overdistension and collapse relate.

objectivesTo compare approaches based on electrical impedance tomography (EIT) (including targeting the crossing point of overdistension/collapse curves, EIT

methodsPost-hoc analysis of 29 patients with COVID-19-related ARDS from cohorts of two Dutch hospitals. Patients underwent a decremental PEEP trial, while EIT data and esophageal pressure data were recorded. We compared the recommended PEEP, as well as resulting P

resultsTargeting EIT

conclusionsTargeting EIT

Indexed as

Acute respiratory distress syndromeElectrical impedance tomographyEsophageal pressureMechanical ventilationPositive end-expiratory pressureRespiratory mechanics

Identifiers

PMID41866609
PMCPMC13006482

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.