Evidence map›Paper›PMID 41866450›Full record

ArticleNeuroscience bulletin2026

Neuronal and Glial YAP/TAZ in the Spinal Cord Contribute to the Development of Bone Cancer Pain in Mice.

Bo Peng, Xiaqing Lin, Jiang-Jian Hu, Huabao Liao, Cheng Li, Zhaoyu Li, Xue-Jun Song

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Neuroscience bulletin, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Bo Peng *Department of Medical Neuroscience, School of Medicine, Southern University of Science and Technology, Shenzhen, 518055, China.ORCID https://orcid.org/0009-0008-2228-3079
Xiaqing Lin *Department of Medical Neuroscience, School of Medicine, Southern University of Science and Technology, Shenzhen, 518055, China.ORCID https://orcid.org/0009-0002-5250-3761
Jiang-Jian HuDepartment of Medical Neuroscience, School of Medicine, Southern University of Science and Technology, Shenzhen, 518055, China.
Huabao LiaoDepartment of Medical Neuroscience, School of Medicine, Southern University of Science and Technology, Shenzhen, 518055, China.
Cheng LiDepartment of Medical Neuroscience, School of Medicine, Southern University of Science and Technology, Shenzhen, 518055, China.ORCID https://orcid.org/0009-0004-9141-6286
Zhaoyu LiQueensland Brain Institute, The University of Queensland, Brisbane, 4072, Australia.
Xue-Jun SongDepartment of Medical Neuroscience, School of Medicine, Southern University of Science and Technology, Shenzhen, 518055, China. songxuejun@sustech.edu.cn.ORCID https://orcid.org/0000-0003-4386-9868

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The treatment of bone cancer pain (BCP) remains a major clinical challenge, and the mechanisms underlying BCP remain poorly understood. Here, we report that tumor cell implantation (TCI) led to nuclear accumulation of yes-associated protein (YAP) and transcriptional coactivator with PDZ (postsynaptic density protein 95, PSD-95; discs large, Dlg; zonula occludens-1, ZO-1)-binding motif (TAZ) and up-regulation of their mRNA (messenger ribonucleic acid) expression in Vglut2

Indexed as

Adaptor Proteins, Signal TransducingBone NeoplasmsCancer PainCell Cycle ProteinsNeurogliaNeuronsSpinal CordAnimalsAstrocytesMiceMicrogliaSignal TransductionTranscription FactorsYAP-Signaling ProteinsAdaptor Proteins, Signal TransducingCell Cycle ProteinsTranscription FactorsYap1 protein, mouseYAP-Signaling ProteinsAstrocytesIL-1βIL-6MicrogliaNF-κBTNF-αVglut2+ excitatory neuronsβ-catenin

Identifiers

PMID41866450
PMCPMC13424279

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.